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Anti-HNF1 beta (Polyclonal), ALEXA Fluor 594

Anti-HNF1 beta (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHNF1 beta
SpecificityThis antibody reacts specifically with HNF1 beta
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HNF1 beta
Gene ID6928
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Evidence suggests that HNF-6 may also be a transriptional activator for at least 22 other hepatocyte-enriched genes, HNF-3 (a, HNF-3a, HNF-3a and HNF-3b have also been shown to be involved in gastrulation events such as body axis formation, HNF-3b and HNF-3g regulate the transcription of numerous hepatocyte genes in adult liver, HNF-4 (a and g) and HNF-6 compose, HNF-4a and HNF-4g have been shown to be important for early embryo development, HNF-4a is expressed in liver, HNF-6 has been shown to bind to the promoter of HNF-3b, The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, a homoeprotein family designated the hepatocyte nuclear factor family, and HNF-4g is expressed in each of these tissues except liver, b and g), in part, including cytochrome P450 2C13 and a-1 antitrypsin, kidney, pancreas, small intestine, small intestine and thymus, testis and colon, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation, HNF-1 (a and b)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HNF1 LFB1
Also known asHNF1 beta Polyclonal Antibody
Other nameAnti-HNF1 beta Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHNF1 beta
Short nameAnti-HNF1 beta (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HNF1 b (polyclonal)
Alternative techniquepolyclonals
Identity 11621
Gene HNF1A
Long gene name HNF1 homeobox A
Synonyms gene MODY3 TCF1
Synonyms gene name LF-B1, albumin proximal factor , hepatic, hepatic nuclear factor (HNF1), transcription factor 1
Locus 12q24, 31
Discovery year 1990-02-12
GenBank acession M57732
Entrez gene record 6927
Pubmed identfication 1535333 7795649
RefSeq identity NM_000545
Classification HNF class homeoboxes
Havana BLAST/BLAT OTTHUMG00000151015
Locus Specific Databases Monogenic Diabetes LRG_522

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