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Anti-HOXD9 (Polyclonal), ALEXA Fluor 594

Anti-HOXD9 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHOXD9
SpecificityThis antibody reacts specifically with HOXD9
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HOXD9
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activation of HoxD9 depends on the structure of the target regulatory element, Furthermore, HoxD9 may be a multifunctional transcriptional regulator, HoxD9 transcripts are also detected in the synovial tissue of arthritic mice, In vivo, Specifically, The HoxD9 protein is expressed in the early stages of mouse joint development, The human HoxD9 protein is also differentially expressed in the human cervical cancer cell line HeLa, and results in differential cofactor interaction, as it contains different activation domains, but is not expressed in the normal cervix and may thus play a role in tumorigenesis, but not in osteoarthritis patients, but not in that of normal mice, primarily in the articular cartilage, suggesting that HoxD9 may have a role in the pathology of arthritis, the HoxD9 protein interacts with the autoregulatory and cross-regulatory enhancers of the murine HoxB1 and human HoxD9 genes, the HoxD9 protein interacts with the human control region (HCR) of the HoxD9 gene, the HoxD9 protein is highly expressed in the synoviocytes of patients with rheumatoid arthritis (RA), thus inducing transcription of the HoxD9 promoter, The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asHOXD9 Polyclonal Antibody
Other nameAnti-HOXD9 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHOXD9
Short nameAnti-HOXD9 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HOXD9 (polyclonal)
Alternative techniquepolyclonals
Identity 5140
Gene HOXD9
Long gene name homeobox D9
Synonyms gene HOX4C HOX4
Synonyms gene name homeo box D9
Locus 2q31, 1
Discovery year 1990-06-15
Entrez gene record 3235
Pubmed identfication 1973146 1358459
Classification HOXL subclass homeoboxes
Havana BLAST/BLAT OTTHUMG00000132516

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