Name : Anti-HPV16 E6 protein (2E3) Monoclonal, ALEXA Fluor 594
Supplier : BIOSS MONOCLONAL ANTIBODIES
Price :489
SKU : GEN6894440232
| Type | Conjugated Primary Antibody |
| Conjugated with | ALEXA FLUOR 594 |
| Host organism | Mouse (Mus musculus) |
| Target Protein/Peptide | HPV16 E6 protein |
| Specificity | Highly specific antibody against HPV16 E6 protein |
| Modification | Not modified |
| Clonality | Monoclonal Antibodies |
| Clone | 2E3 |
| Concentration | 1ug per 1ul |
| Antigen Source | KLH conjugated synthetic peptide derived from HPV16 E6 protein |
| Gene ID | 1399 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross Reactive species | Virus |
| Cross Reactive Species details | HPV16 |
| Background information | Approximately 90% of cervical cancers contain HPV DNA of the high risk types, HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types, Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function, The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, The specific interactions of the E6 and E7 proteins with p53 and pRB, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro, correlate with HPV high and low risk classifications, respectively, Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer |
| Purification method | Purified by Protein G |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, Aqueous buffered solution containing 100ug/ml BSA, C for 12 months |
| Excitation emission | 590nm/617nm |
| Synonyms | E6 protein, HPV16 E6, HPV16 E6 protein, HPV16-E6, Human Papilloma Virus, Human papillomavirus type 16, Human papillomavirus type 16 E6, Protein E6, VE6_HPV16, E6 |
| Alternative name 1 | 594 Conjugated, ALEXA FLUOR®, HPV16 E6 protein (2E3) Monoclonal Antibody |
| Alternative name 2 | ALEXA FLUOR 594 Conjugated, HPV16 E6 protein (2E3) Monoclonal anti- |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, specificity and reactivity, Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | HPV16 E6 protein (2E3) Monoclonal |
| Short name | Fluor 594, Anti-HPV16 E6 protein (2E3) Monoclonal |
| Technique | Monoclonals or monoclonal antibodies |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-HPV16 E6 protein (2E3) monoclonal |