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Anti-HRK Antibody

Anti-HRK Antibody size: 100ug 393

Supplier MBS POLYCLONALS 1
Price 393
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HRK
Alternative name2RABBIT ANTI HRK
Alternative name3Lapin ANTI HRK
Alternative name4HRK
Alternative name5N/A
Other names Activator of apoptosis harakiri, BCL2 interacting protein (contains only BH3 domain), BCL2-interacting protein, BH3-interacting domain-containing protein 3, BH3-interacting domain-containing protein 3, Neuronal death protein DP5, activator of apoptosis Hrk, activator of apoptosis harakiri, death protein 5, harakiri, neuronal death protein DP5, activator of apoptosis harakiri
Gene nameHRK
Gene name synonimsN/A
Other gene names BID3, DP5, HARAKIRI, HRK, HRK
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity Despite its predicted molecular weight, HRK is a BH3 only protein of the Bcl-2 family, HRK is thought to have a specific role in initiating neuronal and haematopoietic cell apoptosis, HRK often migrates at 12-15kD, HRK regulates apoptosis through its interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL, _x000D_Aberrant methylation of HRK is frequently detected in primary colorectal cancers, also known as DP5, and in conjunction to the mitochondrial pore forming protein p32, in particular to growth factor deprivation, which promotes Bax dependent apoptosis, HRK This item detects Harakiri (HRK)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for:Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene targetHRK
Short nameAnti-HRK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name BCL2 interacting protein (contains only BH3 domain) (Antibody to), antibody to-harakiri
Alternative techniqueantibodies
Alternative to gene target BCL2 interacting protein (contains only BH3 domain), DP5 and HARAKIRI, HRK and IDBG-59297 and ENSG00000135116 and 8739, HRK and IDBG-633660 and ENSBTAG00000047484 and 787139, Hrk and IDBG-195140 and ENSMUSG00000046607 and 12123, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0006915 and apoptotic process and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0032464 and positive regulation of protein homooli this GO merization and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, harakiri
Identity 5185
Gene HRK
Long gene name BCL2 interacting protein , harakiri
Synonyms gene name BCL2-interacting protein (contains only BH3 domain) , harakiri
Synonyms DP5
Synonyms name death protein 5
Locus 12q24, 22
Discovery year 1999-05-21
GenBank acession U76376
Entrez gene record 8739
Pubmed identfication 9130713
Classification BCL2 homology region 3 (BH3) only
Havana BLAST/BLAT OTTHUMG00000169328

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