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Anti-HSD17B8 (Polyclonal), ALEXA Fluor 594

Anti-HSD17B8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHSD17B8
SpecificityThis antibody reacts specifically with HSD17B8
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HSD17B8
Gene ID7923
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 17beta-HSD8 converts active steroids to their inactive form through its oxidative activity, 17beta-HSD8 is predominantly expressed in placenta, It has also been suggested that low levels of 17beta-HSD proteins may result in an underdeveloped urogenital system, It has been proposed that a reduction in the levels of 17beta-HSD8 may lead to abnormal elevations in the local level of sex steroids, It is a key player in the inactivation of Estradiol and Testosterone, and pancreas, endometrium and prostate but can also be found in liver, ovary and kidney, which can lead to recessive renal cystic disease, with lowest levels found in testis, 17beta-HSD8 belongs to the 17beta-HSD family of proteins that regulate the availability of steroids within a tissue
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HKE6 D6S2245E RING2 KE6 H2-KE6 SDR30C1
Also known asHSD17B8 Polyclonal Antibody
Other nameAnti-HSD17B8 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHSD17B8
Short nameAnti-HSD17B8 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HSD17B8 (polyclonal)
Alternative techniquepolyclonals
Identity 3554
Gene HSD17B8
Long gene name hydroxysteroid 17-beta dehydrogenase 8
Synonyms gene FABGL
Synonyms gene name E coli) like (E, FabG (beta-ketoacyl-[acyl-carrier-protein] reductase, coli) hydroxysteroid (17-beta) dehydrogenase 8
Synonyms name member 1 , short chain dehydrogenase/reductase family 30C
Locus 6p21, 32
Discovery year 2000-06-26
GenBank acession D82061
Entrez gene record 7923
Pubmed identfication 8812499 19027726
RefSeq identity NM_014234
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000031117

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