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Anti-HSH2D (Polyclonal), ALEXA Fluor 594

Anti-HSH2D (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHSH2D
SpecificityThis antibody reacts specifically with HSH2D
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HSH2D
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Considered an adaptor protein, Containing an SH2 domain, HSH2 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 19p13, HSH2 interacts with tyrosine kinases Fes and ACK, HSH2 may also act to attenuate apoptosis through modulating the apoptotic response by promoting mitochondrial stability, HSH2 participates in tyrosine kinase signaling and may be involved in the regulation of cytokine signaling and cytoskeletal reorganization in hematopoietic cells, and weakly expressed in prostate, four PXXP polyproline sequences and two possible tyrosine phosphorylation sites, heart, small intestine and placenta, such as peripheral blood leukocytes, thymus, 11, HSH2 is a 352 amino acid nuclear and cytoplasmic protein that is predominantly expressed in spleen and hematopoietic cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ALX HSH2 FLJ14886
Also known asHSH2D Polyclonal Antibody
Other nameAnti-HSH2D Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHSH2D
Short nameAnti-HSH2D (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-hematopoietic SH2 domain containing (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target HSH2D and IDBG-35350 and ENSG00000196684 and 84941, HSH2D and IDBG-642330 and ENSBTAG00000038154 and 100848273, Hsh2d and IDBG-167646 and ENSMUSG00000062007 and 209488, nuclei, protein binding, this GO :0002903 and negative regulation of B cell apoptotic process and biological process this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0042110 and T cell activation and biological process this GO :0051902 and negative regulation of mitochondrial depolarization and biological process, this GO :0005070: SH3/SH2 adaptor activity, this GO :0005070: SH3/SH2 adaptor activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, hematopoietic SH2 domain containing
Identity 24920
Gene HSH2D
Long gene name hematopoietic SH2 domain containing
Locus 19p13, 11
Discovery year 2004-03-31
GenBank acession AK027792
Entrez gene record 84941
Pubmed identfication 11700021
RefSeq identity NM_032855
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000182256

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