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Anti-HSP90 alpha (Thr5 + Thr7), ALEXA Fluor 594

Anti-HSP90 alpha (Thr5 + Thr7), ALEXA Fluor 594 size: 100 microliters 516

Price 516
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHSP90 alpha Thr5 + Thr7
SpecificityHSP90 alpha (Thr5 + Thr7), These phosphorylation sites are homologous across the listed species
ModificationPhosphorylation
Modification siteThr5 + Thr7
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Cell membrane, Cytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human HSP90 around the phosphorylation site of Thr5/7
Gene ID3320
Swiss ProtP07900
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ATPase cycle and chaperone function, Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, Interacts dynamically with various co-chaperones that modulate its substrate recognition, This cycle probably induces conformational changes in the client proteins, Undergoes a functional cycle that is linked to its ATPase activity, including TNF secretion by monocytes, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction, thereby causing their activation, Molecular chaperone that promotes the maturation
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Hsp89 Hsp90 FLJ31884 HSP90N
Also known asHSP90 alpha (Thr5 + Thr7) Antibody
Other nameAnti-HSP90 alpha (Thr5 + Thr7)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetHSP90 alpha (Thr5 + Thr7)
Short nameAnti-HSP90 alpha (Thr5 + Thr7) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HSP90 a (Thr5 and Thr7)
Identity 5253
Gene HSP90AA1
Long gene name heat shock protein 90 alpha family class A member 1
Synonyms gene HSPC1 HSPCA
Synonyms gene name alpha heat shock 90kDa protein 1, alpha heat shock protein 90kDa alpha (cytosolic), class A member 1 , heat shock 90kD protein 1
Locus 14q32, 31
Discovery year 1990-06-27
GenBank acession M27024
Entrez gene record 3320
Pubmed identfication 2527334 16269234
RefSeq identity NM_005348
Classification Heat shock 90kDa proteins
Havana BLAST/BLAT OTTHUMG00000171752

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