Name : Anti-HUMAN CD220 Antibody
Supplier : MBS POLYCLONALS 1
Price :818
SKU : GEN6073963042
| Alternative name1 | Anti-RABBIT ANTI HUMAN CD220 |
| Alternative name2 | RABBIT ANTI HUMAN CD220 |
| Alternative name3 | Lapin ANTI Homo sapiens CD220 |
| Alternative name4 | CD220 |
| Alternative name5 | N/A |
| Other names | IR, Insulin receptor, N/A, insulin receptor, insulin receptor, insulin receptor isoform Long preproprotein |
| Gene name | CD220 |
| Gene name synonims | N/A |
| Other gene names | CD220, HHF5, INSR, IR, INSR |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | Polyclonal IgG |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | CD220 is a heterotetrameric membrane glycoprotein consisting of four disulfide linked subunits, CD220 is a member of the tyrosine kinase family of receptors, Neuronal CD220 signalling has been shown to have an important role in energy homeostasis, These effects mostly occur in skeletal muscle, _x000D__x000D_Activation of CD220 leads to a number of cellular effects, also known as Insulin receptor (INRS), and mediates the effects of insulin and IGF-I (insulin-like growth factor-I) through the activation of insulin receptor substrate (IRS) proteins and downstream effector cascades, fat and the liver, including glucose uptake, reproduction and the development of neurodegenerative diseases, the regulation of cell proliferation and gene expression, two alpha subunits and two beta subunits, CD220 This item detects an epitope within in the internal domain of human CD220 |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping | Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for: | Immunohistology - Paraffin (IHC) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | CD220 |
| Short name | Anti-HUMAN CD220 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens CD220 (Antibody to), antibody to-H |
| Alternative technique | antibodies |
| Identity | 6091 |
| Gene | INSR |
| Long gene name | insulin receptor |
| Synonyms | CD220 |
| Locus | 19p13, 2 |
| Discovery year | 1986-01-01 |
| GenBank acession | M10051 |
| Entrez gene record | 3643 |
| Pubmed identfication | 2983222 |
| Classification | CD molecules Fibronectin type III domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000181992 |