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Anti-HUMAN CD49b

Anti-HUMAN CD49b size: 50ug 818

Supplier MBS POLYCLONALS 1
Price 818
Size 50ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN CD49b
Alternative name2RABBIT ANTI HUMAN CD49b
Alternative name3Lapin ANTI Homo sapiens CD49b
Alternative name4CD49b
Alternative name5N/A
Other names CD49 antigen-like family member B, CD49 antigen-like family member B, Collagen receptor, GPIa, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha, VLA2 receptor, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), alpha-2 subunit, alpha-2 subunit, collagen receptor, human platelet alloantigen system 5, integrin, integrin alpha-2, platelet antigen Br, platelet glycoprotein GPIa, platelet membrane glycoprotein Ia, very late activation protein 2 receptor, integrin alpha-2
Gene nameCD49b
Gene name synonimsN/A
Other gene names BR, CD49B, CD49B, GPIa, GPIa, HPA-5, ITGA2, VLA-2, VLAA2, ITGA2
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity CD49b has been identified on a subset of regulatory T cells which produce interleukin 10 (IL-10), CD49b is a 160kD glycoprotein that non-covalently associates with integrin beta 1 (CD29) to form the VLA-2 complex, Originally identified on activated human T lymphocytes, _x000D__x000D_VLA-2 has been linked to cardiovascular disease, also known as integrin alpha-2 (ITGA2), and functions as a cell surface receptor for many types of collagen, cancer development and metastasis, this complex was subsequently shown to be present on a wide variety of cell types including fibroblasts and platelets, CD49b This item detects an epitope within the extracellular domain of human CD49b, _x000D_This complex is involved in cell adhesion and cell-surface mediated signalling
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration7mg/ml, IgG concentration 0
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for:Immunohistology - Paraffin (IHC)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Gene targetCD49b
Short nameAnti-HUMAN CD49b
Alternative name sapiens CD49b, antibody to-H
Identity 1684
Gene CD49B
Long gene name integrin subunit alpha 2
Synonyms gene name alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) , integrin
Synonyms CD49b ITGA2
Synonyms name alpha 2 subunit of VLA-2 receptor
Locus 5q11, 2
Discovery year 1991-08-06
Entrez gene record 3673
RefSeq identity NM_002203
Classification Integrin alpha subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000131165
Locus Specific Databases LRG_1001

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