| Alternative name1 | Anti-RABBIT ANTI HUMAN CTGF:Biotin |
| Alternative name2 | RABBIT ANTI HUMAN CTGF:Biotin |
| Alternative name3 | Lapin ANTI Homo sapiens CTGF:Biotin |
| Alternative name4 | CTGF |
| Alternative name5 | N/A |
| Other names | CCN family member 2, CCN family member 2, Connective tissue growth factor, Hypertrophic chondrocyte-specific protein 24, IBP-8, IGF-binding protein 8, IGFBP-8, Insulin-like growth factor-binding protein 8, connective tissue growth factor, connective tissue growth factor, hypertrophic chondrocyte-specific protein 24, insulin-like growth factor-binding protein 8, connective tissue growth factor |
| Gene name | CTGF |
| Gene name synonims | N/A |
| Other gene names | CCN2, CCN2, CTGF, HCS24, HCS24, IBP-8, IGF-binding protein 8, IGFBP-8, IGFBP8, IGFBP8, NOV2, CTGF |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | Polyclonal IgG |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | CTGF induces extracellular matrix formation, CTGF promotes the adhesion of epithelial cells and fibroblasts, _x000D__x000D_CTGF is a heparin-binding pleiotropic growth factor involved in chondrogenesis and potentially skeletogenesis, a 323 amino acid polypeptide and member of the CCN family of secreted cysteine rich regulatory proteins, and also promotes endothelial cell survival, and has also been implicated in wound healing, and interacts with several other growth factors, implicating CTGF in angiogenesis, including the deposition of excessive collagen in fibrotic diseases, including transforming growth factor beta (TGF-beta), migration and adhesion, stimulates integrin expression, vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMPs), which is produced by vascular endothelial and umbilical vein cells, CTGF This item specifically recognises human CTGF (connective tissue growth factor) |
| Purification method | N/A |
| Form/Appearance | Biotin (Purified IgG conjugated to Biotin - lyophilised) |
| Concentration | 1 miligram per 1 mililiter after reconstitution, IgG concentration 0 |
| Storage and shipping | After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for: | ELISA (EIA), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Conjugation | Biotinylated |
| Gene target | CTGF: |
| Short name | Anti-HUMAN CTGF: Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | Biotin |
| Alternative name | sapiens connective tissue growth factor:biotinilated (Antibody to), antibody to-H |
| Alternative technique | antibodies |
| Alternative to gene target | CCN2 and HCS24 and IGFBP8 and NOV2, CTGF and IDBG-633353 and ENSBTAG00000006367 and 281103, CTGF and IDBG-96631 and ENSG00000118523 and 1490, Ctgf and IDBG-138628 and ENSMUSG00000019997 and 14219, Extracellular, heparin binding, this GO :0001502 and cartilage condensation and biological process this GO :0001503 and ossification and biological process this GO :0001525 and angiogenesis and biological process this GO :0001558 and regulation of cell growth and biological process this GO :0001894 and tissue homeostasis and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001968 and fibronectin binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005801 and cis- this GO lgi network and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006260 and DNA replication and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008544 and epidermis development and biological process this GO :0009611 and response to wounding and biological process this GO :0009749 and response to glucose and biological process this GO :0010260 and organ senescence and biological process this GO :0010467 and gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016477 and cell migration and biological process this GO :0030154 and cell differentiation and biological process this GO :0030324 and lung development and biological process this GO :0032330 and regulation of chondrocyte differentiation and biological process this GO :0032355 and response to estradiol and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0034059 and response to anoxia and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035988 and chondrocyte proliferation and biological process this GO :0043200 and response to amino acid and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050867 and positive regulation of cell activation and biological process this GO :0051385 and response to mineralocorticoid and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0060401 and cytosolic calcium ion transport and biological process this GO :0060452 and positive regulation of cardiac muscle contraction and biological process this GO :0060548 and negative regulation of cell death and biological process this GO :0061448 and connective tissue development and biological process this GO :0070278 and extracellular matrix constituent secretion and biological process this GO :0070318 and positive regulation of G0 to G1 transition and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070542 and response to fatty acid and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process, this GO :0001968: fibronectin binding, this GO :0001968: fibronectin binding and also this GO :0005178: integrin binding and also this GO :0005515: protein binding and also this GO :0005520: insulin-like growth factor binding and also this GO :0008083: growth factor activity and also this GO :0008201: heparin binding, this GO :0005178: integrin binding, this GO :0005515: protein binding, this GO :0005520: insulin-like growth factor binding, this GO :0008083: growth factor activity, this GO :0008201: heparin binding, connective tissue growth factor |
| Identity | 2500 |
| Gene | CTGF |
| Long gene name | connective tissue growth factor |
| Synonyms | IGFBP8 CCN2 |
| Locus | 6q23, 2 |
| Discovery year | 1992-12-01 |
| GenBank acession | X78947 |
| Entrez gene record | 1490 |
| Pubmed identfication | 1654338 |
| RefSeq identity | NM_001901 |
| Classification | CYR61/CTGF/NOV matricellular proteins |
| Havana BLAST/BLAT | OTTHUMG00000015573 |
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