Name : Anti-human Fibrinogen (4F7) Monoclonal, ALEXA Fluor 594
Supplier : BIOSS MONOCLONAL ANTIBODIES
Price :489
SKU : GEN4801419906
| Type | Conjugated Primary Antibody |
| Conjugated with | ALEXA FLUOR 594 |
| Host organism | Mouse (Mus musculus) |
| Target Protein/Peptide | human Fibrinogen |
| Specificity | Highly specific antibody against human Fibrinogen |
| Modification | Not modified |
| Clonality | Monoclonal Antibodies |
| Clone | 4F7 |
| Concentration | 1ug per 1ul |
| Antigen Source | Fibrinogen from human plasma |
| Gene ID | 2243 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross Reactive species | Human (Homo sapiens) |
| Cross Reactive Species details | No significant cross reactivity is observed |
| Background information | All chains are connected with each other by a number of disulfide bonds, All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases, An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A, Fibrinogen activation is also involved in pathogenesis of inflammation, Fibrinogen clotting underlies pathogenesis of MI, Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, In this way fibrinogen is converted into fibrin, It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases, The normal fibrinogen concentration in plasma is about 3 mg/ml, and Rapold H, beta and gamma, et al, et al), respectively, since fibrin is the main substrate for thrombus formation, thromboembolism and thromboses of arteries and veins, tumor growth and many other diseases, which by means of polymerization forms a fibrin clot, Fibrinogen is the main protein of blood coagulation system, J |
| Purification method | Purified by Protein G |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, Aqueous buffered solution containing 100ug/ml BSA, C for 12 months |
| Excitation emission | 590nm/617nm |
| Synonyms | FGA protein, FGB, FGG, FIBA_HUMAN, Fib2, Fibrin alpha chain , Fibrinogen A alpha polypeptide chain, Fibrinogen B alpha polypeptide, Fibrinogen G alpha polypeptide, Fibrinogen alpha chain, Fibrinogen beta chain, Fibrinogen gamma chain, MGC104327, MGC119422, MGC119423, MGC119425, MGC120405, FGA, Fibrinogen A alpha polypeptide |
| Alternative name 1 | 594 Conjugated, ALEXA FLUOR®, human Fibrinogen (4F7) Monoclonal Antibody |
| Alternative name 2 | ALEXA FLUOR 594 Conjugated, human Fibrinogen (4F7) Monoclonal anti- |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, specificity and reactivity, Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | Fibrinogen (4F7) Monoclonal |
| Short name | Fluor 594, Anti-human Fibrinogen (4F7) Monoclonal |
| Technique | Monoclonals or monoclonal antibodies |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, sapiens Fibrinogen (4F7) monoclonal, antibody to-H |