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Anti-HUMAN Mcl-1 Antibody

Anti-HUMAN Mcl-1 Antibody size: 100ug 475

Supplier MBS POLYCLONALS 1
Price 475
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN Mcl-1
Alternative name2RABBIT ANTI HUMAN Mcl-1
Alternative name3Lapin ANTI Homo sapiens Mcl-1
Alternative name4Mcl-1
Alternative name5N/A
Other names Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, Induced myeloid leukemia cell differentiation protein Mcl-1, bcl-2-like protein 3, bcl-2-related protein EAT/mcl1, induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, myeloid cell leukemia ES, myeloid cell leukemia sequence 1 (BCL2-related), induced myeloid leukemia cell differentiation protein Mcl-1 isoform 3
Gene nameMcl-1
Gene name synonimsN/A
Other gene names BCL2L3, BCL2L3, Bcl2-L-3, EAT, MCL1, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, MCL1
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity Interaction between these two antagonistic variants can act to regulate cell survival, MCL-1S has been identified as a pro-apoptotic splice variant of MCL-1L, _x000D__x000D_The MCL-1 protein, _x000D__x000D_This item recognises both the MCL-1L (38kDa) and MCL-1S (30kDa) isoforms of MCL-1, an anti-apoptotic member of the Bcl-2 family of proteins, and expressed in many different cell lines, first identified in differentiating ML-1 myeloid cells, has since been isolated in two distinct isoforms, known as MCL-1 long (MCL-1L) and MCL-1 short (MCL-1S), localised to intracellular membranes and particularly mitochondrial membranes, missing the transmembrane and BH1 and BH2 (Bcl-2 homology) domains, tissues and a variety of tumours, Mcl-1 This item recognises an epitope within the central region (IN) of human Myeloid cell leukaemia sequence 1 (MCL-1), _x000D_
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for:Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene targetMcl-1
Short nameAnti-HUMAN Mcl-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens Mcl-1 (Antibody to), antibody to-H
Alternative techniqueantibodies
Identity 6943
Gene MCL1
Long gene name BCL2 family apoptosis regulator
Synonyms gene name myeloid cell leukemia sequence 1 (BCL2-related) myeloid cell leukemia 1
Synonyms BCL2L3 Mcl-1
Locus 1q21, 2
Discovery year 1993-11-09
GenBank acession BC017197
Entrez gene record 4170
Pubmed identfication 7682708 7835896
RefSeq identity NM_021960
Classification BCL2 family
Havana BLAST/BLAT OTTHUMG00000034867

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