| Also known as | NGFR |
| Other names | Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, NGF receptor, TNFR superfamily, Tumor necrosis factor receptor superfamily member 16, low affinity nerve growth factor receptor, low affinity neurotrophin receptor p75NTR, low-affinity nerve growth factor receptor, member 16, member 16), nerve growth factor receptor, p75 ICD, p75 ICD, tumor necrosis factor receptor superfamily member 16, nerve growth factor receptor (TNFR superfamily |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | NGFR |
| Gene name synonims | N/A |
| Other gene names | CD271, Gp80-LNGFR, NGF receptor, NGFR, TNFRSF16, TNFRSF16, p75(NTR), p75NTR, NGFR |
| Clonality | Monoclonal |
| Immunoglobulin isotype | k, Mouse IgG1 |
| Clone | 4, ME20 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Neuronal Growth Factor Receptor |
| Purification method | 0, This product contains 0, and 0, pH 7, 0 ml PBS (20mM), 1% sodium azide (NaN3), 14M NaCl, 2% gelatin, 3, Purified via protein A in 1 |
| Form/Appearance | Biotin |
| Concentration | N/A |
| Storage and shipping | Antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol has to added and the vial must be stored at -20°, C, Lyophilized antibodies may be transported at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage |
| Tested applications: | Immunohistochemistry (IHC) |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, 6, Biotin conjugates can be detected by horseradish peroxidase, Homo sapiens sapiens), humans , ssp |
| Conjugation | Biotinylated |
| Gene target | 4) IgG1), NGFR ME20 |
| Short name | 4) (mouse IgG1), Anti- NGFR (Clone ME20 |
| Host | mouse |
| Isotype | IgG1 |
| Label | Biotin |
| Species | Humans, Human |
| Alternative name | sapiens nerve growth factor receptor biotinilated (clonality ME20, 4) (mouse IgG1), antibody to-H |
| Alternative technique | immunoglobulins |
| Alternative to gene target | CD271 and Gp80-LNGFR and p75(NTR) and p75NTR and TNFRSF16, NGFR and IDBG-57653 and ENSG00000064300 and 4804, NGFR and IDBG-638806 and ENSBTAG00000020979 and 353110, Ngfr and IDBG-209608 and ENSMUSG00000000120 and 18053, nerve growth factor binding, nuclei, this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005035 and death receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007417 and central nervous system development and biological process this GO :0009986 and cell surface and cellular component this GO :0010468 and regulation of gene expression and biological process this GO :0012501 and programmed cell death and biological process this GO :0016048 and detection of temperature stimulus and biological process this GO :0017137 and Rab GTPase binding and molecular function this GO :0021675 and nerve development and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0031293 and membrane protein intracellular domain proteolysis and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0040037 and negative regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0042488 and positive regulation of odontogenesis of dentin-containing tooth and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043588 and skin development and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048406 and nerve growth factor binding and molecular function this GO :0050770 and regulation of axonogenesis and biological process this GO :0050771 and negative regulation of axonogenesis and biological process this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0051799 and negative regulation of hair follicle development and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097481 and neuronal postsynaptic density and cellular component this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process this GO :2001273 and regulation of glucose import in response to insulin stimulus and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005035: death receptor activity and also this GO :0005515: protein binding and also this GO :0017137: Rab GTPase binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0048406: nerve growth factor binding, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005035: death receptor activity, this GO :0005515: protein binding, this GO :0017137: Rab GTPase binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0048406: nerve growth factor binding, nerve growth factor receptor |
| Identity | 7809 |
| Gene | NGFR |
| Long gene name | nerve growth factor receptor |
| Synonyms gene name | member 16) , nerve growth factor receptor (TNFR superfamily |
| Synonyms | TNFRSF16 CD271 p75NTR |
| Synonyms name | low affinity nerve growth factor receptor TNFR superfamily, member 16 |
| Locus | 17q21, 33 |
| Discovery year | 2001-06-22 |
| GenBank acession | M14764 |
| Entrez gene record | 4804 |
| Pubmed identfication | 3022937 3006050 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT | OTTHUMG00000161495 |
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