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Anti-HUMAN NOTCH 2

Anti-HUMAN NOTCH 2 size: 0.05 ml 464

Supplier MBS POLYCLONALS 1
Price 464
Size 0.05 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN NOTCH 2
Alternative name2RABBIT ANTI HUMAN NOTCH 2
Alternative name3Lapin ANTI Homo sapiens NOTCH 2
Alternative name4NOTCH 2
Alternative name5N/A
Other names N/A, Neurogenic locus notch homolog protein 2, Notch homolog 2, neurogenic locus notch homolog protein 2, notch 2, neurogenic locus notch homolog protein 2 isoform 2
Gene nameNOTCH 2
Gene name synonimsN/A
Other gene names AGS2, HJCYS, NOTCH2, Notch 2, hN2, hN2, NOTCH2
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity Activation results in cleavage and translocation of the Notch intracellular domain (NICD) to the nucleus, Jagged1 and Jagged2, Notch 2 is a type 1 transmembrane protein that is activated by Delta1, Notch 2 mutations can also be oncogenic, _x000D__x000D_Notch 2 activation results in differentiation and proliferation in many cells, _x000D__x000D_Recently Notch 2 mutations have been shown to exist in a minority of patients suffering from Alagille syndrome (AGS), a dominant, an important signalling protein which is critical for embryonic development, for example in B-cell chronic lymphocytic leukaemia (B-CLL), functioning in the maturation of CD8 thymocytes and the development of Marginal Zone B cells, in particular in myeloid cell differentiation, multi-system disorder, where it functions as a transcriptional regulator, NOTCH 2 This item detects Notch 2
Purification methodN/A
Form/AppearanceSerum (Serum - liquid)
ConcentrationN/A
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for: ELISA (EIA), Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Gene targetNOTCH 2
Short nameAnti-HUMAN NOTCH 2
Alternative name sapiens NOTCH 2, antibody to-H
Identity 31862
Gene NOTCH2NL
Long gene name notch 2 N-terminal like
Synonyms gene name Notch homolog 2 (Drosophila) N-terminal like
Synonyms N2N
Locus 1q21, 1
Discovery year 2004-12-02
Entrez gene record 388677
Pubmed identfication 14673143
RefSeq identity NM_203458
Havana BLAST/BLAT OTTHUMG00000013754

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