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Anti-HUMAN PDGF BB HOMODIMER

Anti-HUMAN PDGF BB HOMODIMER size: 100ug 569

Supplier MBS POLYCLONALS 1
Price 569
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN PDGF BB HOMODIMER
Alternative name2RABBIT ANTI HUMAN PDGF BB HOMODIMER
Alternative name3Lapin ANTI Homo sapiens PDGF BB HOMODIMER
Alternative name4PDGF
Alternative name5N/A
Other names B chain, PDGF, PDGF subunit B, PDGF-2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, Proto-oncogene c-Sis, becaplermin, beta polypeptide (oncogene SIS), platelet-derived growth factor, platelet-derived growth factor 2, platelet-derived growth factor B chain, platelet-derived growth factor beta polypeptide, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), platelet-derived growth factor subunit B, proto-oncogene c-Sis, platelet-derived growth factor subunit B isoform 1 preproprotein
Gene namePDGF
Gene name synonimsN/A
Other gene names PDGF subunit B, PDGF-2, PDGF2, PDGF2, PDGFB, SIS, SIS, SSV, c-sis, PDGFB
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity Naturally occurring active forms of PDGF exist as dimers of two alpha chains (AA), PDGFs are potent mitogens for a variety of cells including those of the connective tissue, The expression of PDGF-BB is associated with autocrine growth stimulation and the formation of various tumour types, a disulphide-linked beta-chain homodimer and member of the PDGF family, all of which signal through the high-affinity PDGF-Ralpha receptor, an infiltrating skin tumour arising from a translocation occurring between chromosome 22 (the location of the PDGFB gene) and chromosome 17 (the location of the COL1A1 gene), and are involved in several biological processes including chemotaxis, and the latter two of which can also signal through the PDGF-Rbeta receptor, blood and smooth muscle cells, bone and cartilage, hyperplasia and embryonic neurogenesis, or a combination of both chains (AB), released from platelet alpha-granules following trauma/platelet activation, two beta chains (BB), which results in the generation of the COL1A1-PDGFB chimeric protein, with several studies focusing on dermatofibrosarcoma protuberans (DP), PDGF This item is specific for human PDGF-BB (Platelet derived growth factor B chain)
Purification methodN/A
Form/AppearancePurified (Purified IgG - lyophilised)
Concentration0 mg/ml after reconstitution, IgG concentration 1
Storage and shipping After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius
Tested for: ELISA (EIA), Functional Assay (FA), Western Blot (WB), Immunohistology - Paraffin (IHC)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Gene targetPDGF BB HOMODIMER
Short nameAnti-HUMAN PDGF BB HOMODIMER
Alternative name sapiens PDGF BB HOMODIMER, antibody to-H

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