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Anti-HUMAN PRESENILIN-1 (LOOP) Antibody

Anti-HUMAN PRESENILIN-1 (LOOP) Antibody size: 100ul 531

Supplier MBS POLYCLONALS 1
Price 531
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN PRESENILIN-1 (LOOP)
Alternative name2RABBIT ANTI HUMAN PRESENILIN-1 (LOOP)
Alternative name3Lapin ANTI Homo sapiens PRESENILIN-1 (LOOP)
Alternative name4PRESENILIN-1
Alternative name5N/A
Other names Presenilin-1, Protein S182, presenilin 1, presenilin-1, presenilin-1 isoform I-467
Gene nameN/A
Gene name synonimsN/A
Other gene names AD3, AD3, FAD, PS-1, PS-1, PS1, PS1, PS1-CTF12, PSEN1, PSNL1, S182, PSEN1
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity PSEN1 is an essential component of the gamma-secretase complex, PSEN2, Pen-2 (PEN2), This endoprotease complex plays a vital role in the evolutionarily conserved Notch signaling pathway, _x000D__x000D_Mutations of presenilin-1 are associated with early onset Alzheimer's disease, along with APH-1 (APH-1A or APH-1B), an integral membrane protein that is widely expressed, and nicastrin (NCSTN), by catalyzing the intramembrane S3 cleavage of ligand-activated Notch receptor proteins (Notch1-4), especially in brain tissue, resulting in the generation and release of an activated NICD fragment, which then translocates to the nucleus and activates the transcription of downstream effector genes, PRESENILIN-1 This item recognises presenilin-1 (PSEN1)
Purification methodN/A
Form/AppearanceSerum (Serum - liquid)
ConcentrationN/A
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for: Immunoprecipitation (IP), Western Blot (WB), Immunohistology - Frozen (IHC)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene targetPRESENILIN-1 (LOOP)
Short nameAnti-HUMAN PRESENILIN-1 (LOOP) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens PRESENILIN-1 (LOOP) (Antibody to), antibody to-H
Alternative techniqueantibodies

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