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Anti-HUMAN TOPBP1 Antibody

Anti-HUMAN TOPBP1 Antibody size: 50ug 475

Supplier MBS POLYCLONALS 1
Price 475
Size 50ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI HUMAN TOPBP1
Alternative name2RABBIT ANTI HUMAN TOPBP1
Alternative name3Lapin ANTI Homo sapiens TOPBP1
Alternative name4TOPBP1
Alternative name5N/A
Other names DNA topoisomerase 2-binding protein 1, DNA topoisomerase 2-binding protein 1, DNA topoisomerase II-beta-binding protein 1, DNA topoisomerase II-beta-binding protein 1, DNA topoisomerase II-binding protein 1, DNA topoisomerase II-binding protein 1, TopBP1, topoisomerase (DNA) II binding protein 1, DNA topoisomerase 2-binding protein 1
Gene nameTOPBP1
Gene name synonimsN/A
Other gene names KIAA0259, TOP2BP1, TOPBP1, TopBP1, TOPBP1
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity Mus101 (<, Rad4 (<, TopBP1 co-localizes with BRCA1 and is an important factor in minimising stalled replication forks and double-strand breaks (DSB), _x000D_Studies indicate a role for TopBP1 in DNA replication through interaction with DNA polymerase E, a phosphoprotein upregulated during the S phase of the cell cycle, and in DNA repair response to ionizing radiation damage, cerevisiae<, in S phase DNA checkpoint control, melanogaster<, pombe<, thereby maintaining genomic integrity, which shares sequence homology with Dpb11 (<, ), ), ) and Cut5 (Xenopus), /i>, /i>, /i>, D, S, S, TOPBP1 This product specifically recognizes human TopBP1 (DNA Topoisomerase II Binding Protein I), i>, i>, i>
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, DO NOT FREEZE, Shelf Life: 12 months from date of dispatch, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for: Immunoprecipitation (IP), Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene targetTOPBP1
Short nameAnti-HUMAN TOPBP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens TOPBP1 (Antibody to), antibody to-H
Alternative techniqueantibodies
Identity 17008
Gene TOPBP1
Long gene name topoisomerase (DNA) II binding protein 1
Synonyms KIAA0259 TOP2BP1
Locus 3q22, 1
Discovery year 2004-06-21
GenBank acession AB019397
Entrez gene record 11073
Pubmed identfication 9461304 9039502
RefSeq identity NM_007027
Classification BRCA1 B complex
Havana BLAST/BLAT OTTHUMG00000159773

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