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Anti-Humanin (Polyclonal), ALEXA Fluor 594

Anti-Humanin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHumanin
SpecificityThis antibody reacts specifically with Humanin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Humanin
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Humanin acts as a ligand for formyl peptide receptor-like 1 (FPRL1) with APP and utilizes its neuroprotective effects by inhibiting FPRL1 access to APP, Humanin expression levels may be dependent on defects in energy production in muscles with mitochondrial abnormalities, Humanin is mainly expressed in the kidney, Humanin protects neuronal cells from damage caused by Alzheimer's disease genes, The peptide has been detected in muscles of patients with the mitochondrial disease chronic progressive external ophthalmoplegia (CPEO), The peptide prevents Bax translocation from cytosol to mitochondria, The secreted protein is a neuroprotective factor against death induced by several different types of Alzheimer's disease genes, an endogenous anti-apoptotic peptide against Alzheimer disease-related insults, consists of 24 amino acids, heart, liver, specifically APP (amyloid precursor protein), testis and skeletal muscles, Humanin
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HN 16S
Also known asHumanin Polyclonal Antibody
Other nameAnti-Humanin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHumanin
Short nameAnti-Humanin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Humanin (polyclonal)
Alternative techniquepolyclonals
Identity 7471
Gene MT-RNR2
Long gene name mitochondrially encoded 16S RNA
Synonyms gene MTRNR2
Synonyms name humanin formyl-humanin
Locus mitochondria
Discovery year 1989-10-12
Entrez gene record 4550
Pubmed identfication 12009529 12445508
RefSeq identity NC_012920
Classification Endogenous ligands Mitochondrially encoded ribosomal RNAs

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