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Anti-HYPE/HIP13 (Polyclonal), ALEXA Fluor 594

Anti-HYPE/HIP13 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHYPE/HIP13
SpecificityThis antibody reacts specifically with HYPE/HIP13
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HYPE
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, HYPE also contains two tetratricopeptide repeats (TPR), HYPE is thought to interact with Huntingtin, The gene that encodes HYPE is located on chromosome 12, Trisomy 12p leads to facial development defects, a protein which induces neurodegeneration when mutated, achondrogenesis and Kniest dysplasia, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy, which encodes over 1, which may be involved in protein-protein interaction, 100 genes within 132 million bases and makes up about 4, 5% of the human genome, Huntingtin yeast partner E is a 458 amino acid single-pass membrane protein
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HYPE HIP13
Also known asHYPE/HIP13 Polyclonal Antibody
Other nameAnti-HYPE/HIP13 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHYPE/HIP13
Short nameAnti-HYPE/HIP13 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HYPE/HIP13 (polyclonal)
Alternative techniquepolyclonals
Identity 18416
Gene FICD
Long gene name FIC domain containing
Synonyms name coli) , huntingtin interacting protein 13 fic S-phase protein cell division homolog (E
Locus 12q23, 3
Discovery year 2007-12-04
GenBank acession AF049611
Entrez gene record 11153
Pubmed identfication 9700202
RefSeq identity NM_007076
Havana BLAST/BLAT OTTHUMG00000169569

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