Name : Anti-IBTK (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7793802619
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | IBTK |
| Specificity | This antibody reacts specifically with IBTK |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human IBTK |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription, IBTK is a encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | DKFZP564B116 BTBD26 |
| Also known as | IBTK Polyclonal Antibody |
| Other name | Anti-IBTK Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | IBTK |
| Short name | Anti-IBTK (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-inhibitor on Bruton agammaglobulinemia tyrosine kinase (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BTBD26 and BTKI, IBTK and IDBG-630145 and ENSBTAG00000026716 and 540885, IBTK and IDBG-93669 and ENSG00000005700 and 102724346, Ibtk and IDBG-188976 and ENSMUSG00000035941 and 108837, nuclei, protein tyrosine kinase inhibitor activity, this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0016020 and membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030292 and protein tyrosine kinase inhibitor activity and molecular function this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0061099 and negative regulation of protein tyrosine kinase activity and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0019901: protein kinase binding and also this GO :0030292: protein tyrosine kinase inhibitor activity, this GO :0019901: protein kinase binding, this GO :0030292: protein tyrosine kinase inhibitor activity, 25998, 102725056, inhibitor of Bruton agammaglobulinemia tyrosine kinase |
| Identity | 17853 |
| Gene | IBTK |
| Long gene name | inhibitor of Bruton tyrosine kinase |
| Synonyms gene | BTKI |
| Synonyms gene name | Bruton agammaglobulinemia tyrosine kinase inhibitor inhibitor of Bruton agammaglobulinemia tyrosine kinase |
| Locus | 6q14, 1 |
| Discovery year | 2003-08-29 |
| GenBank acession | AF235049 |
| Entrez gene record | 25998 |
| Pubmed identfication | 11577348 |
| RefSeq identity | NM_015525 |
| Classification | BTB domain containing Ankyrin repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000015102 |