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Anti-IBTK (Polyclonal), ALEXA Fluor 594

Anti-IBTK (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIBTK
SpecificityThis antibody reacts specifically with IBTK
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human IBTK
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription, IBTK is a encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DKFZP564B116 BTBD26
Also known asIBTK Polyclonal Antibody
Other nameAnti-IBTK Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIBTK
Short nameAnti-IBTK (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-inhibitor on Bruton agammaglobulinemia tyrosine kinase (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BTBD26 and BTKI, IBTK and IDBG-630145 and ENSBTAG00000026716 and 540885, IBTK and IDBG-93669 and ENSG00000005700 and 102724346, Ibtk and IDBG-188976 and ENSMUSG00000035941 and 108837, nuclei, protein tyrosine kinase inhibitor activity, this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0016020 and membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030292 and protein tyrosine kinase inhibitor activity and molecular function this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0061099 and negative regulation of protein tyrosine kinase activity and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0019901: protein kinase binding and also this GO :0030292: protein tyrosine kinase inhibitor activity, this GO :0019901: protein kinase binding, this GO :0030292: protein tyrosine kinase inhibitor activity, 25998, 102725056, inhibitor of Bruton agammaglobulinemia tyrosine kinase
Identity 17853
Gene IBTK
Long gene name inhibitor of Bruton tyrosine kinase
Synonyms gene BTKI
Synonyms gene name Bruton agammaglobulinemia tyrosine kinase inhibitor inhibitor of Bruton agammaglobulinemia tyrosine kinase
Locus 6q14, 1
Discovery year 2003-08-29
GenBank acession AF235049
Entrez gene record 25998
Pubmed identfication 11577348
RefSeq identity NM_015525
Classification BTB domain containing Ankyrin repeat domain containing
Havana BLAST/BLAT OTTHUMG00000015102

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