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Anti-ID4 (Polyclonal), ALEXA Fluor 594

Anti-ID4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideID4
SpecificityThis antibody reacts specifically with ID4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ID4
Gene ID3400
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Due to the absence of the basic region, Id2 (4), Id3 and Id4 (5), It has been shown that expression of each of the Id proteins is strongly dependent on growth factor activation and that reduction of Id mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation, Since Id1 inhibits DNA binding of E12 and Myo D, The Id-type proteins thus appear to negatively regulate DNA binding of bHLH proteins, They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins (1â, Under conditions that facilitate muscle cell differentiation, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, it apparently functions to inhibit muscle-specific gene expression, the Id protein levels fall, the resulting heterodimers cannot bind DNA, which in turn activate myogenic differentiation, &euro, &euro, &ldquo, &ldquo, 3), 5), Members of the Id family of basic helix-loop-helix (bHLH) proteins include Id1 (1â
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms bHLHb27
Also known asID4 Polyclonal Antibody
Other nameAnti-ID4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetID4
Short nameAnti-ID4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-ID4 (polyclonal)
Alternative techniquepolyclonals
Identity 5363
Gene ID4
Long gene name HLH protein , inhibitor of DNA binding 4
Synonyms gene name dominant negative helix-loop-helix protein , inhibitor of DNA binding 4
Synonyms name inhibitor of differentiation 4
Locus 6p22, 3
Discovery year 1995-02-13
GenBank acession U16153
Entrez gene record 3400
Pubmed identfication 7665172
RefSeq identity NM_001546
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000014333

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