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Anti-IDH1 (Polyclonal), ALEXA Fluor 594

Anti-IDH1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIDH1
SpecificityThis antibody reacts specifically with IDH1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human IDH1/Isocitrate dehydrogenase
Gene ID3417
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Ca2+ can bind to IDHC as a complex with isocitrate, During this process, IDHC catalyzes the third step of the citric acid cycle, IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle, The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock, The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, acting as a competitive inhibitor of Mg2+, either NADH or NADPH is produced along with CO2, forming ?ketoglutarate and CO2 in a two step reaction, which involves the oxidative decarboxylation of isocitrate, while the second step involves the production of ?ketoglutarate, The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asIDH1 Polyclonal Antibody
Other nameAnti-IDH1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIDH1
Short nameAnti-IDH1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-IDH1 (polyclonal)
Alternative techniquepolyclonals
Identity 5382
Gene IDH1
Long gene name cytosolic , isocitrate dehydrogenase (NADP(+)) 1
Synonyms gene name isocitrate dehydrogenase 1 (NADP+), soluble isocitrate dehydrogenase 1 (NADP+)
Locus 2q34
Discovery year 2001-06-22
Entrez gene record 3417
RefSeq identity NM_005896
Havana BLAST/BLAT OTTHUMG00000132943
Locus Specific Databases LRG_610

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