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Anti-IFNAR1(Ser535+Ser538), ALEXA Fluor 594

Anti-IFNAR1(Ser535+Ser538), ALEXA Fluor 594 size: 100 microliters 516

Price 516
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIFNAR1 Ser535 + Ser538
SpecificityThis antibody reacts specifically with IFNAR1(Ser535+Ser538)
ModificationPhosphorylation
Modification siteSer535+Ser538
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538
Gene ID3454
Swiss ProtP17181
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, Can also transduce IFNB signals without the help of IFNAR2, Receptor for interferons alpha and beta, STAT proteins and IFNR alpha- and beta-subunits themselves, TYK2, and not activating the Jak-STAT pathway, Associates with IFNAR2 to form the type I interferon receptor
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms IFRC
Also known asIFNAR1(Ser535+Ser538) Antibody
Other nameAnti-IFNAR1(Ser535+Ser538)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetIFNAR1(Ser535+Ser538)
Short nameAnti-IFNAR1(Ser535+Ser538) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, b and omega) receptor 1(Ser535+Ser538), antibody to-interferon (a
Alternative to gene target AVP and IFN-alpha-REC and IFNAR and IFNBR and IFRC, IFNAR1 and IDBG-2095 and ENSG00000142166 and 3454, IFNAR1 and IDBG-629846 and ENSBTAG00000021819 and 282257, Ifnar1 and IDBG-176038 and ENSMUSG00000022967 and 15975, Plasma membranes, beta and omega) receptor 1, protein binding, this GO :0004904 and interferon receptor activity and molecular function this GO :0004905 and type I interferon receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009615 and response to virus and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0042110 and T cell activation and biological process this GO :0045087 and innate immune response and biological process this GO :0045351 and type I interferon biosynthetic process and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0051607 and defense response to virus and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process, this GO :0004904: interferon receptor activity, this GO :0004904: interferon receptor activity and also this GO :0004905: type I interferon receptor activity and also this GO :0005515: protein binding, this GO :0004905: type I interferon receptor activity, this GO :0005515: protein binding, interferon (alpha
Identity 5432
Gene IFNAR1
Long gene name interferon alpha and beta receptor subunit 1
Synonyms gene IFNAR
Synonyms gene name beta and omega) receptor 1 , interferon (alpha
Locus 21q22, 11
Discovery year 1986-01-01
Entrez gene record 3454
Pubmed identfication 8181059
Classification Interferon receptors
Havana BLAST/BLAT OTTHUMG00000065126

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