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Anti-IGF2BP3 (Polyclonal), ALEXA Fluor 594

Anti-IGF2BP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIGF2BP3
SpecificityThis antibody reacts specifically with IGF2BP3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Insulin-like growth factor 2 mRNA-binding protein 3
Gene ID10643
Swiss ProtO00425
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binds to beta-actin/ACTB and MYC transcripts, Binds to the 3'-UTR of CD44 mRNA and stabilizes it, Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs, It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation, This transcript 'caging' into mRNPs allows mRNA transport and transient storage, hence promotes cell adhesion and invadopodia formation in cancer cells, RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms IMP-3 CT98 IMP3
Also known asIGF2BP3 Polyclonal Antibody
Other nameAnti-IGF2BP3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIGF2BP3
Short nameAnti-IGF2BP3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-insulin-like growth factor 2 messenger RNA binding protein 3 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target CT98 and IMP-3 and IMP3 and KOC and KOC1 and VICKZ3, IGF2BP3 and IDBG-630336 and ENSBTAG00000019406 and 539650, IGF2BP3 and IDBG-9675 and ENSG00000136231 and 10643, Igf2bp3 and IDBG-146190 and ENSMUSG00000029814 and 140488, mRNA 5'-UTR binding, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0003676 and nucleic acid binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003730 and mRNA 3'-UTR binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006412 and translation and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0010467 and gene expression and biological process this GO :0017148 and negative regulation of translation and biological process this GO :0042035 and regulation of cytokine biosynthetic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045182 and translation regulator activity and molecular function this GO :0048027 and mRNA 5'-UTR binding and molecular function this GO :0051028 and mRNA transport and biological process, this GO :0000166: nucleotide binding, this GO :0000166: nucleotide binding and also this GO :0003676: nucleic acid binding and also this GO :0003723: RNA binding and also this GO :0003730: mRNA 3'-UTR binding and also this GO :0005515: protein binding and also this GO :0044822: poly(A) RNA binding and also this GO :0045182: translation regulator activity and also this GO :0048027: mRNA 5'-UTR binding, this GO :0003676: nucleic acid binding, this GO :0003723: RNA binding, this GO :0003730: mRNA 3'-UTR binding, this GO :0005515: protein binding, this GO :0044822: poly(A) RNA binding, this GO :0045182: translation regulator activity, this GO :0048027: mRNA 5'-UTR binding, insulin-like growth factor 2 mRNA binding protein 3
Identity 28868
Gene IGF2BP3
Long gene name insulin like growth factor 2 mRNA binding protein 3
Synonyms gene name insulin-like growth factor 2 mRNA binding protein 3
Synonyms name IGF II mRNA binding protein 3 cancer/testis antigen 98
Locus 7p15, 3
Discovery year 2006-02-09
GenBank acession AF117108
Entrez gene record 10643
Pubmed identfication 9891060 9178771
RefSeq identity NM_006547
Classification RNA binding motif containing
Havana BLAST/BLAT OTTHUMG00000128445

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