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Anti-IGFBP3 (Polyclonal), ALEXA Fluor 594

Anti-IGFBP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIGFBP3
SpecificityThis antibody reacts specifically with IGFBP3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from human IGFBP3
Gene ID3486
Swiss ProtP17936
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R, They alter the interaction of IGFs with their cell surface receptors, IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms IBP3 BP-53
Also known asIGFBP3 Polyclonal Antibody
Other nameAnti-IGFBP3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIGFBP3
Short nameAnti-IGFBP3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-insulin-like growth factor binding protein 3 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BP-53 and IBP3, IGFBP3 and IDBG-15809 and ENSG00000146674 and 3486, IGFBP3 and IDBG-633994 and ENSBTAG00000003994 and 282261, Igfbp3 and IDBG-148893 and ENSMUSG00000020427 and 16009, metal ion binding, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001968 and fibronectin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0008160 and protein tyrosine phosphatase activator activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0010906 and regulation of glucose metabolic process and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016942 and insulin-like growth factor binding protein complex and cellular component this GO :0031994 and insulin-like growth factor I binding and molecular function this GO :0040008 and regulation of growth and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043568 and positive regulation of insulin-like growth factor receptor signaling pathway and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0044342 and type B pancreatic cell proliferation and biological process this GO :0045663 and positive regulation of myoblast differentiation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001968: fibronectin binding, this GO :0001968: fibronectin binding and also this GO :0005515: protein binding and also this GO :0005520: insulin-like growth factor binding and also this GO :0008160: protein tyrosine phosphatase activator activity and also this GO :0031994: insulin-like growth factor I binding and also this GO :0046872: metal ion binding, this GO :0005515: protein binding, this GO :0005520: insulin-like growth factor binding, this GO :0008160: protein tyrosine phosphatase activator activity, this GO :0031994: insulin-like growth factor I binding, this GO :0046872: metal ion binding, insulin-like growth factor binding protein 3
Identity 5472
Gene IGFBP3
Long gene name insulin like growth factor binding protein 3
Synonyms gene name insulin-like growth factor binding protein 3
Synonyms name growth hormone-dependent binding protein acid stable subunit of the 140 K IGF complex binding protein 53 binding protein 29 IGF-binding protein 3
Locus 7p12, 3
Discovery year 1991-07-09
Entrez gene record 3486
Pubmed identfication 1695633
RefSeq identity NM_001013398
Classification Insulin like growth factor binding proteins
Havana BLAST/BLAT OTTHUMG00000023769
Locus Specific Databases LRG_68

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