Name : Anti-IGSF1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7558212085
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | IGSF1 |
| Specificity | This antibody reacts specifically with IGSF1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human IGSF1 |
| Gene ID | 3547 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Expression is high in pancreas, IGSF1 has been found to interact with several members of the ACVR family and possibly some members of the BMPR group, IGSF1 has been shown to act as a coreceptor in inhibin signaling, IGSF1 may be found at very low levels in brain, Isoform 3 has been detected in pituitary gland, Isoform 3 is believed to be expressed as a secreted form, May reduce or inhibit activin A signaling and is believed to be necessary in the mediation of specific effects of inhibin B on activin-stimulated transcription, There are 3 known isoforms of IGSF1, colon, fetal lung and fetal kidney, however, it does not appear to be a high-affinity inhibin receptor by itself, muscle, ovary, prostate and small intestine show only moderate expression, testis and fetal liver, thymus, while heart, with 1 and 2 likely being multi-pass membrane proteins, IGSF1 is a highly glycolylated immunoglobulin domain-containing protein |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA0364 IGDC1 IGCD1 INHBP MGC75490 PGSF2 |
| Also known as | IGSF1 Polyclonal Antibody |
| Other name | Anti-IGSF1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | IGSF1 |
| Short name | Anti-IGSF1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, member 1 (polyclonal), antibody to-immunoglobulin superfamily |
| Alternative technique | polyclonals |
| Alternative to gene target | CHTE and IGCD1 and IGDC1 and INHBP and p120 and PGSF2, DNA-templated and biological process this GO :0007165 and signal transduction and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0034711 and inhibin binding and molecular function, Extracellular, IGSF1 and IDBG-630834 and ENSBTAG00000046476 and 100125775, IGSF1 and IDBG-86329 and ENSG00000147255 and 3547, Igsf1 and IDBG-144491 and ENSMUSG00000031111 and 209268, inhibin binding, member 1, this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0006355 and regulation of transcription, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0015026: coreceptor activity and also this GO :0034711: inhibin binding, this GO :0005515: protein binding, this GO :0015026: coreceptor activity, this GO :0034711: inhibin binding, immunoglobulin superfamily |
| Identity | 5948 |
| Gene | IGSF1 |
| Long gene name | immunoglobulin superfamily member 1 |
| Synonyms gene name | immunoglobulin superfamily, member 1 |
| Locus | Xq25 |
| Discovery year | 1997-10-27 |
| GenBank acession | AF034198 |
| Entrez gene record | 3547 |
| Pubmed identfication | 9521868 9729118 |
| Classification | Immunoglobulin like domain containing |
| Havana BLAST/BLAT | OTTHUMG00000022406 |
| Locus Specific Databases | Mental Retardation database LRG_840 |