Name : Anti-IGSF6 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4777163899
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | IGSF6 |
| Specificity | This antibody reacts specifically with IGSF6 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human IGSF6 |
| Gene ID | 10261 |
| Swiss Prot | O95976 |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Expressed in spleen, IGSF6 (immunoglobulin superfamily, IGSF6 is induced by TNF?and GM-CSF in dendritic cells and downregulated by ionomycin and PMA in monocytes, IGSF6 may function as a co-receptor in the antigen uptake complex or dendritic cell recirculation and is encoded by a gene located on human chromosome 16p12, a locus associated with inflammatory bowel disease, also known as DORA, dendritic cells, growth factor signaling and cell adhesion, is a novel 241 amino acid single-pass type I membrane protein that contains one Ig-like C2-type (immunoglobulin-like) domain, member 6), peripheral blood lymphocytes and lymph node, 2, Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | DORA |
| Also known as | IGSF6 Polyclonal Antibody |
| Other name | Anti-IGSF6 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | IGSF6 |
| Short name | Anti-IGSF6 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, member 6 (polyclonal), antibody to-immunoglobulin superfamily |
| Alternative technique | polyclonals |
| Alternative to gene target | DORA, IGSF6 and IDBG-19352 and ENSG00000140749 and 10261, IGSF6 and IDBG-638411 and ENSBTAG00000018869 and 100140740, Igsf6 and IDBG-208694 and ENSMUSG00000035004 and 80719, Plasma membranes, member 6, protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, immunoglobulin superfamily |
| Identity | 5953 |
| Gene | IGSF6 |
| Long gene name | immunoglobulin superfamily member 6 |
| Synonyms gene name | immunoglobulin superfamily, member 6 |
| Locus | 16p12, 2 |
| Discovery year | 2000-06-05 |
| GenBank acession | AJ223183 |
| Entrez gene record | 10261 |
| Pubmed identfication | 9809579 |
| Classification | V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000090709 |