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Anti-IHH (Polyclonal), ALEXA Fluor 594
Anti-IHH (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489
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BIOSS POLYCLONAL ANTIBODIES
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489
Size
100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | IHH |
| Specificity | This antibody reacts specifically with IHH |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human IHH |
| Gene ID | 3549 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Ihh induces the expression of parathyroid hormone-related protein (PTHRP) and is implicated in endochondral ossification, It binds to the patched (PTC) receptor, possibly regulating the balance between growth and ossification of the developing bones, to activate the transcription of target genes, which functions in association with smoothened (SMO), Ihh is an intercellular signalling peptide essential for a variety of patterning events during development |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | HHG2 BDA1 |
| Also known as | IHH Polyclonal Antibody |
| Other name | Anti-IHH Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | IHH |
| Short name | Anti-IHH (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Indian hedgehog (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BDA1 and HHG2, BT, Extracellular, IHH and IDBG-81274 and ENSG00000163501 and 3549, Ihh and IDBG-169082 and ENSMUSG00000006538 and 16147, peptidase activity, this GO :0001501 and skeletal system development and biological process this GO :0001503 and ossification and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001708 and cell fate specification and biological process this GO :0001763 and morphogenesis of a branching structure and biological process this GO :0001944 and vasculature development and biological process this GO :0001947 and heart looping and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003382 and epithelial cell morphogenesis and biological process this GO :0003406 and retinal pigment epithelium development and biological process this GO :0005113 and patched binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006029 and proteoglycan metabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0007154 and cell communication and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007389 and pattern specification process and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0016539 and intein-mediated protein splicing and biological process this GO :0030154 and cell differentiation and biological process this GO :0030704 and vitelline membrane formation and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0031016 and pancreas development and biological process this GO :0032332 and positive regulation of chondrocyte differentiation and biological process this GO :0032355 and response to estradiol and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0033085 and negative regulation of T cell differentiation in thymus and biological process this GO :0033088 and negative regulation of immature T cell proliferation in thymus and biological process this GO :0033089 and positive regulation of T cell differentiation in thymus and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0035988 and chondrocyte proliferation and biological process this GO :0040008 and regulation of growth and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045453 and bone resorption and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045880 and positive regulation of smoothened signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0046639 and negative regulation of alpha-beta T cell differentiation and biological process this GO :0048074 and negative regulation of eye pigmentation and biological process this GO :0048469 and cell maturation and biological process this GO :0048557 and embryonic digestive tract morphogenesis and biological process this GO :0048596 and embryonic camera-type eye morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048745 and smooth muscle tissue development and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0051216 and cartilage development and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0060220 and camera-type eye photoreceptor cell fate commitment and biological process this GO :0060323 and head morphogenesis and biological process this GO :0061053 and somite development and biological process this GO :0072498 and embryonic skeletal joint development and biological process this GO :0090136 and epithelial cell-cell adhesion and biological process, this GO :0005113: patched binding, this GO :0005113: patched binding and also this GO :0005509: calcium ion binding and also this GO :0008233: peptidase activity, this GO :0005509: calcium ion binding, this GO :0008233: peptidase activity, 22104 and IDBG-643926 and ENSBTAG00000008452 and 522714, Indian hedgehog |
| Identity | 5956 |
| Gene | IHH |
| Long gene name | indian hedgehog |
| Synonyms gene name | Indian hedgehog (Drosophila) homolog Indian hedgehog homolog (Drosophila) |
| Locus | 2q35 |
| Discovery year | 1995-03-21 |
| GenBank acession | L38517 |
| Entrez gene record | 3549 |
| Pubmed identfication | 7590746 14770182 |
| RefSeq identity | NM_002181 |
| Havana BLAST/BLAT | OTTHUMG00000154631 |