Name : Anti-IKB epsilon (Ser157) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN6163776164
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | IKB epsilon Ser157 |
| Specificity | This antibody reacts specifically with IKB epsilon (Ser157) |
| Modification | Phosphorylation |
| Modification site | Ser157 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human NFKBIE around the phosphorylation site of Ser157 |
| Gene ID | 4794 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | AP1 (JUN), Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, For some genes, Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, R is an A or G purine, RELA, The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, activation requires NFKB interaction with other transcription factors, and NFAT, and Y is a C or T pyrimidine), or IKBKB) marks them for destruction via the ubiquitination pathway, or NFKBIB), or RELB to form the NFKB complex, or T, such as STAT, thereby allowing activation of the NF-kappa-B complex, which inactivate NF-kappa-B by trapping it in the cytoplasm, NFKB1 or NFKB2 is bound to REL |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | I kappa B epsilon, IKB epsilon, IKB epsilon S, IKB epsilon Ser157, IKBE, IkB E, IkappaBepsilon, MGC72568, NF kappa B inhibitor epsilon, NF kappa BIE, NFKBIE, NFkappa BIE, NFkappaB inhibitor epsilon, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor epsilon, OTTHUMP00000016522, Slc35b2, member B2, p-IKB epsilon S157, p-IKB epsilon Ser157, solute carrier family 35, NFKBIE phospho S157 |
| Also known as | IKB epsilon (Ser157) Polyclonal Antibody |
| Other name | Anti-IKB epsilon (Ser157) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | IKB epsilon (Ser157) |
| Short name | Anti-IKB epsilon (Ser157) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-IKB epsilon (Ser157) (polyclonal) |
| Alternative technique | polyclonals |