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Anti-IKB zeta (Polyclonal), ALEXA Fluor 594

Anti-IKB zeta (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIKB zeta
SpecificityThis antibody reacts specifically with IKB zeta
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human IKB zeta
Gene ID64332
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In vitro, Inhibits DNA-binding of RELA and NFKB1/p50, Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation, Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS, May promote apoptosis, Promotes transcription of LCN2 and DEFB4, Seems also to activate NF-kappa-B-mediated transcription, Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer, is recruited to LCN2 promoters, together with NFKB1/p50 and RELA, upon association with NFKB1/p50 has transcriptional activation activity and, Involved in regulation of NF-kappa-B transcription factor complexes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms IKBZ, IKBZ_HUMAN, IKBzeta, IL-1 inducible nuclear ankyrin-repeat protein, INAP, IkB-zeta, Ikappa B zeta, IkappaBzeta, MAIL, MAIL protein, Molecule possessing ankyrin repeats induced by lipopolysaccharide, NF-kappa-B inhibitor zeta, NFKBIZ, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor zeta, I-kappa-B-zeta
Also known asIKB zeta Polyclonal Antibody
Other nameAnti-IKB zeta Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIKB zeta
Short nameAnti-IKB zeta (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-IKB zeta (polyclonal)
Alternative techniquepolyclonals

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