Name : Anti-IL-15RA (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4291703996
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | IL-15RA |
| Specificity | This antibody reacts specifically with IL-15RA |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human IL-15RA |
| Gene ID | 3601 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | It shares two subunits with the receptor of IL2, The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding, There are nine different isoforms, This forms the basis of many overlapping biological activities of IL15 and IL2, This protein is structurally related to IL2R alpha, This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2, but is capable of binding IL15 with high affinity independent of other subunits, the IL2R beta and IL2R gamma chains, which suggests the distinct roles between IL15 and IL2, IL15RA is a cytokine receptor that specifically binds IL15 with high affinity |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CD215 IL-15RA |
| Also known as | IL-15RA Polyclonal Antibody |
| Other name | Anti-IL-15RA Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | IL-15RA |
| Short name | Anti-IL-15RA (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Interleukin-15RA (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 5978 |
| Gene | IL15RA |
| Long gene name | interleukin 15 receptor subunit alpha |
| Synonyms gene name | alpha , interleukin 15 receptor |
| Locus | 10p15, 1 |
| Discovery year | 1995-08-10 |
| GenBank acession | U31628 |
| Entrez gene record | 3601 |
| Pubmed identfication | 8530383 |
| RefSeq identity | NM_172200 NM_002189 |
| Classification | Sushi domain containing CD molecules Interleukin receptors |
| Havana BLAST/BLAT | OTTHUMG00000017612 |