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Anti-IL-23 (Polyclonal), ALEXA Fluor 594

Anti-IL-23 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIL-23
SpecificityThis antibody reacts specifically with IL-23
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from human IL-23
Gene ID51561
Swiss ProtQ9NPF7
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis, IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues, a heterodimeric cytokine which functions in innate and adaptive immunity, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines, Associates with IL12B to form the IL-23 interleukin
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SGRF IL23P19 IL-23 IL-23A P19
Also known asIL-23 Polyclonal Antibody
Other nameAnti-IL-23 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIL-23
Short nameAnti-IL-23 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Interleukin-23 (polyclonal)
Alternative techniquepolyclonals
Identity 15488
Gene IL23A
Long gene name interleukin 23 subunit alpha
Synonyms gene name alpha subunit p19 , interleukin 23
Synonyms name G-CSF related factor , interleukin-six
Locus 12q13, 3
Discovery year 2001-04-10
GenBank acession AB030000
Entrez gene record 51561
Pubmed identfication 11114383
RefSeq identity NM_016584
Classification Interleukins
Havana BLAST/BLAT OTTHUMG00000187402

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