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Anti-IL1 Receptor I (Polyclonal), ALEXA Fluor 594

Anti-IL1 Receptor I (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIL-1R1
SpecificityThis antibody reacts specifically with IL1 Receptor I
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human IL-1R1
Gene ID3554
Swiss ProtP14778
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex, IL1B and IL1RN, MAPK and other pathways, MYD88, Signaling involves the recruitment of adapter molecules such as TOLLIP, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits, Receptor for IL1A
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms IL1F1 IL-1A IL1-ALPHA
Also known asIL1 Receptor I Polyclonal Antibody
Other nameAnti-IL1 Receptor I Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIL1 Receptor I
Short nameAnti-IL1 Receptor I (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-IL1 Receptor I (polyclonal)
Alternative techniquepolyclonals
Identity 5991
Gene IL1A
Long gene name interleukin 1 alpha
Synonyms gene IL1
Synonyms name preinterleukin 1 alpha hematopoietin-1 pro-interleukin-1-alpha
Locus 2q14, 1
Discovery year 2001-06-22
GenBank acession M28983
Entrez gene record 3552
Pubmed identfication 8188271 2989698
RefSeq identity NM_000575
Classification Endogenous ligands Interleukins
Havana BLAST/BLAT OTTHUMG00000131315

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