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Anti-INPPL1(Tyr1135) (Polyclonal), ALEXA Fluor 594

Anti-INPPL1(Tyr1135) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideINPPL1 Tyr1135
SpecificityThis antibody reacts specifically with INPPL1(Tyr1135)
ModificationPhosphorylation
Modification siteTyr1135
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human SHIP2 around the phosphorylation site of Tyr1135
Gene ID3636
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A second and much more widely expressed PTP with SH2 domains, HCP and SHP), SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, SHPTP2 (also designated PTP1D and Syp), Several groups have independently identified a non transmembrane PTP, and cell migration, designated SHPTP1 (also known as PTP1C, has been identified, metabolic control, such as mitogenic activation, transcription regulation, which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain, The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SHIP2
Also known asINPPL1(Tyr1135) Polyclonal Antibody
Other nameAnti-INPPL1(Tyr1135) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetINPPL1(Tyr1135)
Short nameAnti-INPPL1(Tyr1135) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-inositol polyphosphate phosphatase-like 1(Tyr1135) (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target INPPL1 and IDBG-63291 and ENSG00000165458 and 3636, INPPL1 and IDBG-635082 and ENSBTAG00000019167 and 783833, Inppl1 and IDBG-202184 and ENSMUSG00000032737 and 16332, OPSMD and SHIP2, Plasma membranes, SH2 domain binding, this GO :0001958 and endochondral ossification and biological process this GO :0002376 and immune system process and biological process this GO :0003779 and actin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006006 and glucose metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006661 and phosphatidylinositol biosynthetic process and biological process this GO :0006897 and endocytosis and biological process this GO :0007015 and actin filament organization and biological process this GO :0007155 and cell adhesion and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009791 and post-embryonic development and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030175 and filopodium and cellular component this GO :0032868 and response to insulin and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0043647 and inositol phosphate metabolic process and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046856 and phosphatidylinositol dephosphorylation and biological process this GO :0097178 and ruffle assembly and biological process, this GO :0003779: actin binding, this GO :0003779: actin binding and also this GO :0005515: protein binding and also this GO :0016787: hydrolase activity and also this GO :0017124: SH3 domain binding and also this GO :0042169: SH2 domain binding, this GO :0005515: protein binding, this GO :0016787: hydrolase activity, this GO :0017124: SH3 domain binding, this GO :0042169: SH2 domain binding, inositol polyphosphate phosphatase-like 1
Identity 6080
Gene INPPL1
Long gene name inositol polyphosphate phosphatase like 1
Synonyms name 51C protein SH2 domain-containing inositol 5', -phosphatase 2 phosphatidylinositol 3, 4, 5-trisphosphate 5-phosphatase 2
Locus 11q13, 4
Discovery year 1995-05-12
GenBank acession Y14385
Entrez gene record 3636
Pubmed identfication 8530088
RefSeq identity NM_001567
Classification Phosphoinositide phosphatases Sterile alpha motif domain containing SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000167879

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