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Anti-Integrin alpha 3 (Polyclonal), ALEXA Fluor 594

Anti-Integrin alpha 3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIntegrin alpha 3
SpecificityThis antibody reacts specifically with Integrin alpha 3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsTransmembrane
Antigen SourceKLH conjugated synthetic peptide derived from human Integrin alpha 3
Gene ID3675
Swiss ProtP26006
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration, Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, collagen, epiligrin, formation of invadopodia and matrix degradation processes, laminin, promoting cell invasion, thrombospondin and CSPG4, Integrin alpha-3/beta-1 is a receptor for fibronectin
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CD49c VLA3a VCA-2 GAP-B3
Also known asIntegrin alpha 3 Polyclonal Antibody
Other nameAnti-Integrin alpha 3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIntegrin alpha 3
Short nameAnti-Integrin alpha 3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Integrin a 3 (polyclonal)
Alternative techniquepolyclonals
Identity 6139
Gene ITGA3
Long gene name integrin subunit alpha 3
Synonyms gene MSK18
Synonyms gene name alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) , antigen identified by monoclonal antibody J143 integrin
Synonyms name alpha 3 subunit of VLA-3 receptor antigen CD49C
Locus 17q21, 33
Discovery year 1992-02-27
GenBank acession M59911
Entrez gene record 3675
Pubmed identfication 1655803 9704023
RefSeq identity NM_005501
Classification Integrin alpha subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000161890

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