Name : Anti-Integrin Alpha V + Beta 6, ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3061449634
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Integrin Alpha V + Beta 6 |
| Specificity | This antibody reacts specifically with Integrin Alpha V + Beta 6 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 6 |
| Gene ID | 3685 3694 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Aberrant integrin expression has been found in many epithelial tumours, Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells, Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues, Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target, which mediate cell-cell and cell-extracellular matrix attachments, Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | ITAV_HUMAN, ITGAV, ITGB6, Integrin, Integrin, Integrin alpha-V light chain, Vitronectin receptor subunit alpha, alpha V, alpha V vitronectin receptor, alpha polypeptide, antigen CD51, beta 6, integrin, CD51 |
| Also known as | Integrin Alpha V + Beta 6 Antibody |
| Other name | Anti-Integrin Alpha V + Beta 6 |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Description | Fluor 594 is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The Anti-Integrin Alpha V + Beta 6 |
| Gene target | Integrin Alpha V + Beta 6 |
| Short name | Fluor 594, Anti-Integrin Alpha V + Beta 6 |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Integrin a V and b 6 |