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Anti-Integrin beta 5 (Polyclonal), ALEXA Fluor 594

Anti-Integrin beta 5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIntegrin beta 5
SpecificityThis antibody reacts specifically with Integrin beta 5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Integrin beta 5
Gene ID3693
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature, Due to their weak individual binding, Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function, Integrins are generally present in high concentrations at the cell surface, Integrins bind many different ligands including laminin, They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit, This integrin is found in a variety of cells in most normal tissue, This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated, but, integrins need to cluster and bind in groups in order to effectively bind the ECM, they bind ligands with very low affinity, unlike most other cell surface receptors, Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces, The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asIntegrin beta 5 Polyclonal Antibody
Other nameAnti-Integrin beta 5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIntegrin beta 5
Short nameAnti-Integrin beta 5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Integrin b 5 (polyclonal)
Alternative techniquepolyclonals
Identity 6160
Gene ITGB5
Long gene name integrin subunit beta 5
Synonyms gene name beta 5 , integrin
Locus 3q21, 2
Discovery year 1991-07-30
GenBank acession J05633
Entrez gene record 3693
Pubmed identfication 2211615
RefSeq identity NM_002213
Classification Integrin beta subunits
Havana BLAST/BLAT OTTHUMG00000159432

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