Name : Anti-IQCG (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7630452776
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | IQCG |
| Specificity | This antibody reacts specifically with IQCG |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human IQCG |
| Gene ID | 84223 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | A modest increase in this level can result in a myriad of physiological responses, IQCG exists as two isoforms due to alternatively splicing events, IQCG forms a complex with Nup98, In acute T-lymphoid/myeloid leukemia, NUP98-IQCG complex bind co-activators and/or co-repressors, The level of intracellular calcium is tightly regulated in all eukaryotic cells, Widely distributed in nature, an O-linked glycoprotein and a component of the nuclear pore complex, most of which are mediated by calmodulin (CaM), the IQ domain forms an amphiphilic seven-turn Î, the universal calcium sensor, which suggest a role in transcriptional regulation, ±, -helix capable of binding calmodulin in a Ca2+-independent manner, IQCG is a 443 amino acid protein containing one IQ domain, Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | DKFZp434B227 DRC9 CFAP122 |
| Also known as | IQCG Polyclonal Antibody |
| Other name | Anti-IQCG Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | IQCG |
| Short name | Anti-IQCG (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-IQCG (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 25251 |
| Gene | IQCG |
| Long gene name | IQ motif containing G |
| Synonyms name | dynein regulatory complex subunit 9 |
| Locus | 3q29 |
| Discovery year | 2005-01-19 |
| GenBank acession | AL136889 |
| Entrez gene record | 84223 |
| Pubmed identfication | 11230166 23427265 24362311 |
| RefSeq identity | NM_032263 |
| Classification | Dynein regulatory complex |
| Havana BLAST/BLAT | OTTHUMG00000155408 |