Anti-IQSEC2 (Polyclonal), ALEXA Fluor 594

Anti-IQSEC2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	IQSEC2
Specificity	This antibody reacts specifically with IQSEC2
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human IQSEC2
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), IQSEC2 exists as three isoforms due to alternative splicing events, IQSEC2 is a component of the postsynaptic density at excitatory synapses, IQSEC2 is expressed in brain, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization, Localizing to the cytoplasm, The gene encoding IQSEC2 maps to the human X chromosome, Through the activation of ARF substrates, a condition characterized by decreased intellectual function, and interacts with ARF family members as a guanine nucleotide exchange factor, kidney and small intestine, one PH domain and a SEC7 domain, ovary, pancreas, prostate and liver, with weaker levels of expression in placenta, 478 amino acid protein that belongs to the BRAG family and contains one IQ domain, IQSEC2 is a 1
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	KIAA0522
Also known as	IQSEC2 Polyclonal Antibody
Other name	Anti-IQSEC2 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	IQSEC2
Short name	Anti-IQSEC2 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-IQSEC2 (polyclonal)
Alternative technique	polyclonals
Identity	29059
Gene	IQSEC2
Long gene name	IQ motif and Sec7 domain 2
Synonyms gene	MRX1 MRX78 MRX18
Synonyms gene name	X-linked 1 (non-dysmorphic) mental retardation, X-linked 18 , X-linked 78 mental retardation, mental retardation
Locus	Xp11, 22
Discovery year	2004-08-27
GenBank acession	AB011094
Entrez gene record	23096
Pubmed identfication	9628581 20473311 26793055
RefSeq identity	XM_291345
Classification	X-linked mental retardation
Havana BLAST/BLAT	OTTHUMG00000021608
Locus Specific Databases	Mental Retardation database

Anti-IQSEC2 (Polyclonal), ALEXA Fluor 594

Anti-IQSEC2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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