Name : anti-IRAK Antibody [1F12C1]
Supplier : PROSCIENCE
Price :180
SKU : GEN3800341348
| Gene info | A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently, IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response, IRAK mediates a signaling cascade leading to NF-kB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF), NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS, IRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses |
| Gene names | pelle, IRAK Antibody [1F12C1] : IRAK |
| Antibodie's label | unlabelled serum |
| Purity | IRAK Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in | Mouse |
| Type | Monoclonal |
| Monoclonal | 1F12C1 |
| Immunoglobulin | IgG1 |
| Antigen | Recombinant protein corresponding to amino acids 618 - 712 of human IRAK |
| Immuno application | Western Blot, immuno-histo-chemistry, ELISA |
| Antibody advice | Antibody can also be used for immunohistochemistry starting at 2, 5 ug/mL, RAK antibody can be used for Western blot at 1 - 2 ug/mL |
| Suspention, pH, azide | 02% sodium azide, IRAK Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at | stable for one year, IRAK monoclonal antibody can be stored at -20 grades C |
| Works with | Mouse, Human |
| Omim nr | 8928535 |
| Ncbi nr | P51617 |
| Vial with antibody | in solution |
| Quantity per ml | 1 mg/mL |
| NCBI GENE nr | 3654 |
| GENE symbol | IRAK1 |
| Antigene name | interleukin-1 receptor-associated kinase 1 |
| Source | homo sapiens |
| Protein nr | P51617 |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target | IRAK [1F12C1] |
| Short name | anti-IRAK Antibody [1F12C1] |
| Technique | antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-IRAK (Antibody to) [1F12C1] |
| Alternative technique | antibodies |
| Identity | 6112 |
| Gene | IRAK1 |
| Long gene name | interleukin 1 receptor associated kinase 1 |
| Synonyms | IRAK pelle |
| Locus | Xq28 |
| Discovery year | 1998-06-22 |
| GenBank acession | L76191 |
| Entrez gene record | 3654 |
| Pubmed identfication | 9374458 8599092 |
| Havana BLAST/BLAT | OTTHUMG00000024228 |
| Locus Specific Databases | Mental Retardation database |