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Anti-IRF6 (Polyclonal), ALEXA Fluor 594

Anti-IRF6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIRF6
SpecificityThis antibody reacts specifically with IRF6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human IRF6
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, IRF-1 functions as an activator of interferon transcription, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3 gamma p48 and IFN consensus sequence-binding protein (ICSBP), In addition, The two factors are structurally related, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion, particularly in their N-terminal regions, which confer DNA binding specificity, while IRF-2 binds to the same cis elements and represses IRF-1 action, Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms OFC6 VWS1
Also known asIRF6 Polyclonal Antibody
Other nameAnti-IRF6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIRF6
Short nameAnti-IRF6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-interferon regulatory factor 6 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030216 and keratinocyte differentiation and biological process this GO :0043588 and skin development and biological process this GO :0043616 and keratinocyte proliferation and biological process this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0048468 and cell development and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, IRF6 and IDBG-106452 and ENSG00000117595 and 3664, IRF6 and IDBG-638354 and ENSBTAG00000002849 and 614253, Irf6 and IDBG-209073 and ENSMUSG00000026638 and 54139, LPS and OFC6 and PIT and PPS and PPS1 and VWS and VWS1, nuclei, protein binding, this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000975: regulatory region DNA binding, this GO :0000975: regulatory region DNA binding and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, interferon regulatory factor 6
Identity 6121
Gene IRF6
Long gene name interferon regulatory factor 6
Synonyms gene VWS LPS
Synonyms gene name Van der Woude syndrome
Locus 1q32, 2
Discovery year 1997-10-16
GenBank acession AL022398
Entrez gene record 3664
Pubmed identfication 12219090
RefSeq identity NM_006147
Havana BLAST/BLAT OTTHUMG00000036521

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