Filters

Anti-IRGM (Polyclonal), ALEXA Fluor 594

Anti-IRGM (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIRGM
SpecificityThis antibody reacts specifically with IRGM
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human IRGM
Gene ID345611
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information IRGM deficient mice show defects with intracellular microbial killing, IRGM has been shown to be required for host defences against a broad range of intracellular pathogens, IRGM is primarily expressed in all cells derived from B-cell lineages, More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli, Specifically, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation, and is highly expressed in macrophages following IFN-gamma stimulation, belonging to the GTPase superfamily, phagosome maturation and autophagy, IRGM belongs to a family of interferon-gamma inducible GTPases
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LRG47 LRG-47 IFI1
Also known asIRGM Polyclonal Antibody
Other nameAnti-IRGM Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIRGM
Short nameAnti-IRGM (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, M (polyclonal), antibody to-immunity-related GTPase family
Alternative techniquepolyclonals
Alternative to gene target IFI47 and IDBG-645396 and ENSBTAG00000015727 and 521987, IRGM and IDBG-306231 and ENSG00000237693 and 345611, Ifi47 and IDBG-262893 and ENSMUSG00000078920 and 15953, M, Plasma membranes, acting on acid anhydrides, acting on acid anhydrides, acting on acid anhydrides and molecular function this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0042995 and cell projection and cellular component this GO :0045087 and innate immune response and biological process, hydrolase activity, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000421 and autophagic vacuole membrane and cellular component this GO :0001891 and pha this GO cytic cup and cellular component this GO :0005525 and GTP binding and molecular function this GO :0006914 and autophagy and biological process this GO :0006954 and inflammatory response and biological process this GO :0016020 and membrane and cellular component this GO :0016817 and hydrolase activity, this GO :0005525: GTP binding, this GO :0005525: GTP binding and also this GO :0016817: hydrolase activity, this GO :0016817: hydrolase activity, immunity-related GTPase family
Identity 29597
Gene IRGM
Long gene name immunity related GTPase M
Synonyms gene IRGM1
Synonyms gene name M1 , immunity-related GTPase family
Locus 5q33, 1
Discovery year 2005-02-21
GenBank acession BC038539
Entrez gene record 345611
Pubmed identfication 7561525 14576437
RefSeq identity NM_001145805
Havana BLAST/BLAT OTTHUMG00000163647

Similar products

Subscribe to our Newsletter