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Anti-IRS-2 (Polyclonal), ALEXA Fluor 594

Anti-IRS-2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideIRS-2
SpecificityThis antibody reacts specifically with IRS-2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human IRS-2
Gene ID8660
Swiss ProtQ9Y4H2
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Each IRS is believed to have different functions, Four members of the IRS family have been described, Summary: This gene encodes the insulin receptor substrate 2, The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, a cytoplasmic signaling molecule that mediates effects of insulin, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment, however, insulin-like growth factor 1, the distinct physiological roles of each IRS are unclear, The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms IRS2, Insulin receptor substrate 2, IRS-2
Also known asIRS-2 Polyclonal Antibody
Other nameAnti-IRS-2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetIRS-2
Short nameAnti-IRS-2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-IRS-2 (polyclonal)
Alternative techniquepolyclonals

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