Name : Anti-ISLR2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2828019078
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ISLR2 |
| Specificity | This antibody reacts specifically with ISLR2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human ISLR2 |
| Gene ID | 57611 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | All LRR repeats contain a variable segment and a highly conserved segment, ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), ISLR2 exists as a homomultimer and is essential for axon extension during neural development, The gene encoding ISLR2 maps to human chromosome 15q24, a LRRCT domain and one LRRNT domain, allowing it to accommodate several leucine residues within a tightly packed core, also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), horseshoe fold, is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, the latter of which accounts for 11 or 12 residues of the entire LRR motif, &circ, «, /â, 1, The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic &, aring |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA1465 |
| Also known as | ISLR2 Polyclonal Antibody |
| Other name | Anti-ISLR2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ISLR2 |
| Short name | Anti-ISLR2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-immunoglobulin superfamily containing leucine-rich repeat 2 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | Cell surfaces, ISLR2 and IDBG-21815 and ENSG00000167178 and 57611, ISLR2 and IDBG-647871 and ENSBTAG00000002661 and 617436, Islr2 and IDBG-171681 and ENSMUSG00000051243 and 320563, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0045773 and positive regulation of axon extension and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, immunoglobulin superfamily containing leucine-rich repeat 2 |
| Identity | 29286 |
| Gene | ISLR2 |
| Long gene name | immunoglobulin superfamily containing leucine rich repeat 2 |
| Locus | 15q24, 1 |
| Discovery year | 2006-02-16 |
| Entrez gene record | 57611 |
| Pubmed identfication | 10819331 12975309 |
| RefSeq identity | NM_020851 |
| Classification | Immunoglobulin like domain containing |
| Havana BLAST/BLAT | OTTHUMG00000137624 |