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Anti-ITPR3 (Polyclonal), ALEXA Fluor 594
Anti-ITPR3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489
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BIOSS POLYCLONAL ANTIBODIES
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489
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100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | ITPR3 |
| Specificity | This antibody reacts specifically with ITPR3 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human ITPR3 |
| Gene ID | 3710 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | IP3R, IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, IP3R-II and IP3R-III, Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), The inositol 1, Three IP3 receptor subtypes have been described and are designated IP3R-I, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types, but is also expressed at high levels in the liver, growth factors and neurotransmitters, which convert phosphatidylinositol-4, 4, 4, 5 bisphosphate into IP3 and diacylglycerol (DAG), 5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, 5-triphosphate receptor, Inositol 1 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | IP3R3 |
| Also known as | ITPR3 Polyclonal Antibody |
| Other name | Anti-ITPR3 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | ITPR3 |
| Short name | Anti-ITPR3 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, classification 3 (polyclonal), 4, 5-trisphosphate receptor, antibody to-inositol 1 |
| Alternative technique | polyclonals |
| Alternative to gene target | IP3R and IP3R3, ITPR3 and IDBG-629118 and ENSBTAG00000013245 and 281879, ITPR3 and IDBG-82972 and ENSG00000096433 and 3710, Itpr3 and IDBG-156294 and ENSMUSG00000042644 and 16440, inositol 1, nuclei, this GO :0000822 and inositol hexakisphosphate binding and molecular function this GO :0005216 and ion channel activity and molecular function this GO :0005218 and intracellular ligand-gated calcium channel activity and molecular function this GO :0005220 and inositol 1, this GO :0000822: inositol hexakisphosphate binding, this GO :0000822: inositol hexakisphosphate binding and also this GO :0005216: ion channel activity and also this GO :0005218: intracellular ligand-gated calcium channel activity and also this GO :0005220: inositol 1, this GO :0005216: ion channel activity, this GO :0005218: intracellular ligand-gated calcium channel activity, this GO :0005220: inositol 1, this GO :0005262: calcium channel activity, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0035091: phosphatidylinositol binding, this GO :0043533: inositol 1, this GO :0070679: inositol 1, type 3, 3, 3, 3, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 5 tetrakisphosphate binding, 5 tetrakisphosphate binding and also this GO :0070679: inositol 1, 5 tetrakisphosphate binding and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045177 and apical part of cell and cellular component this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050796 and regulation of insulin secretion and biological process this GO :0050913 and sensory perception of bitter taste and biological process this GO :0050916 and sensory perception of sweet taste and biological process this GO :0050917 and sensory perception of umami taste and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051592 and response to calcium ion and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060291 and long-term synaptic potentiation and biological process this GO :0060402 and calcium ion transport into cytosol and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0070679 and inositol 1, 5 trisphosphate binding, 5 trisphosphate binding, 5 trisphosphate binding and molecular function, 5-trisphosphate receptor, 5-trisphosphate-sensitive calcium-release channel activity, 5-trisphosphate-sensitive calcium-release channel activity and also this GO :0005262: calcium channel activity and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0035091: phosphatidylinositol binding and also this GO :0043533: inositol 1, 5-trisphosphate-sensitive calcium-release channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005640 and nuclear outer membrane and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005903 and brush border and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007596 and blood coagulation and biological process this GO :0007613 and memory and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0031095 and platelet dense tubular network membrane and cellular component this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043209 and myelin sheath and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043533 and inositol 1, inositol 1 |
| Identity | 6182 |
| Gene | ITPR3 |
| Long gene name | inositol 1, 4, 5-trisphosphate receptor type 3 |
| Synonyms gene name | inositol 1, type 3 , type 3 inositol 1, 4, 4, 5-triphosphate receptor, 5-trisphosphate receptor |
| Locus | 6p21, 31 |
| Discovery year | 1991-06-05 |
| GenBank acession | D26351 |
| Entrez gene record | 3710 |
| Pubmed identfication | 8081734 8288584 |
| RefSeq identity | NM_002224 |
| Classification | Inositol 1, 4, 5-triphosphate receptors Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT | OTTHUMG00000014532 |