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Anti-Jarid2/Jumonji (Polyclonal), ALEXA Fluor 594

Anti-Jarid2/Jumonji (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideJarid2/Jumonji
SpecificityThis antibody reacts specifically with Jarid2/Jumonji
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human Jarid2/Jumonji
Gene ID3720
Swiss ProtQ92833
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes, Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5, Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes, In cardiac cells, In embryonic stem cells, Participates in the negative regulation of cell proliferation signaling, including heart and liver development, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases, neural tube fusion process and hematopoiesis, thereby playing a key role in differentiation of embryonic stem cells and normal development, Regulator of histone methyltransferase complexes that plays an essential role in embryonic development
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms JARID2, Jumonji/ARID domain-containing protein 2, Protein Jumonji, JMJ
Also known asJarid2/Jumonji Polyclonal Antibody
Other nameAnti-Jarid2/Jumonji Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetJarid2/Jumonji
Short nameAnti-Jarid2/Jumonji (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, AT rich interactive domain 2/Jumonji (polyclonal), antibody to-jumonji
Alternative techniquepolyclonals

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