Name : Anti-JIP3 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6967267165
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | JIP3 |
| Specificity | This antibody reacts specifically with JIP3 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human JIP3 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Expressed in a variety of tissues, Human JIP-3, JIP-3 (JNK-interacting protein 3), JIP-3 forms homo- or heterooligomeric complexes that can interact with several components of the JNK signaling pathway, Multiple isoforms of JIP-3 exist due to alternative splicing events, also known as JSAP1 or MAPK8IP3 (Mitogen-activated protein kinase 8-interacting protein 3), including brain and heart, is a 1, shares 69% similarity with its mouse counterpart, suggesting a conserved role between species, thereby functioning as a regulator of kinesin-dependent axonal transport that may also play a role in scaffold formation within neuronal cells, which may be phosphorylated upon DNA damage, 336 amino acid protein that localizes to the cytoplasm and belongs to the JIP family, The JNK-interacting proteins (JIPs) are a family of scaffold proteins that mediate JNK signaling by organizing specific components of the MAPK cascade together to form a functional JNK signaling molecule |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA1066 JSAP1 JIP3 syd |
| Also known as | JIP3 Polyclonal Antibody |
| Other name | Anti-JIP3 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | JIP3 |
| Short name | Anti-JIP3 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-JIP3 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 6884 |
| Gene | MAPK8IP3 |
| Long gene name | mitogen-activated protein kinase 8 interacting protein 3 |
| Synonyms name | homolog of Drosophila Sunday driver 2 |
| Locus | 16p13, 3 |
| Discovery year | 2000-08-22 |
| GenBank acession | AB028989 |
| Entrez gene record | 23162 |
| Pubmed identfication | 10523642 10629060 |
| RefSeq identity | NM_001040439 |
| Havana BLAST/BLAT | OTTHUMG00000128637 |