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Anti-JIP3 (Polyclonal), ALEXA Fluor 594

Anti-JIP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideJIP3
SpecificityThis antibody reacts specifically with JIP3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human JIP3
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Expressed in a variety of tissues, Human JIP-3, JIP-3 (JNK-interacting protein 3), JIP-3 forms homo- or heterooligomeric complexes that can interact with several components of the JNK signaling pathway, Multiple isoforms of JIP-3 exist due to alternative splicing events, also known as JSAP1 or MAPK8IP3 (Mitogen-activated protein kinase 8-interacting protein 3), including brain and heart, is a 1, shares 69% similarity with its mouse counterpart, suggesting a conserved role between species, thereby functioning as a regulator of kinesin-dependent axonal transport that may also play a role in scaffold formation within neuronal cells, which may be phosphorylated upon DNA damage, 336 amino acid protein that localizes to the cytoplasm and belongs to the JIP family, The JNK-interacting proteins (JIPs) are a family of scaffold proteins that mediate JNK signaling by organizing specific components of the MAPK cascade together to form a functional JNK signaling molecule
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1066 JSAP1 JIP3 syd
Also known asJIP3 Polyclonal Antibody
Other nameAnti-JIP3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetJIP3
Short nameAnti-JIP3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-JIP3 (polyclonal)
Alternative techniquepolyclonals
Identity 6884
Gene MAPK8IP3
Long gene name mitogen-activated protein kinase 8 interacting protein 3
Synonyms name homolog of Drosophila Sunday driver 2
Locus 16p13, 3
Discovery year 2000-08-22
GenBank acession AB028989
Entrez gene record 23162
Pubmed identfication 10523642 10629060
RefSeq identity NM_001040439
Havana BLAST/BLAT OTTHUMG00000128637

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