Anti-JMJD1B (Polyclonal), ALEXA Fluor 594

Anti-JMJD1B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	JMJD1B
Specificity	This antibody reacts specifically with JMJD1B
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human JMJD1B
Gene ID	51780
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	5qNCA (5q Nuclear Co-Activator) or C5orf7, Eptopic expression of JMJD1B exhibits growth suppressive activities, Expressed in a wide variety of tissues, JMJD1B functions as a histone demethylase and, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif, The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias, This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia, This suggests that JMJD1B plays a central role in the histone code, also known as KDM3B, demethylates lysine-9 of Histone H3, further supporting a role for JMJD1B in tumor suppression, is a member of the JHDM2 histone demethylase family of proteins, using iron as a cofactor, JMJD1B (jumonji domain containing 1B)
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	KIAA1082 NET22
Also known as	JMJD1B Polyclonal Antibody
Other name	Anti-JMJD1B Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	JMJD1B
Short name	Anti-JMJD1B (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-JMJD1B (polyclonal)
Alternative technique	polyclonals
Identity	1337
Gene	KDM3B
Long gene name	lysine demethylase 3B
Synonyms gene	C5orf7 JMJD1B
Synonyms gene name	chromosome 5 open reading frame 7 jumonji domain containing 1B lysine (K)-specific demethylase 3B
Locus	5q31, 2
Discovery year	2000-07-21
GenBank acession	AF251039
Entrez gene record	51780
Pubmed identfication	15138608
RefSeq identity	NM_016604
Classification	Lysine demethylases
Havana BLAST/BLAT	OTTHUMG00000163469

Anti-JMJD1B (Polyclonal), ALEXA Fluor 594

Anti-JMJD1B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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