Anti-JNK1 + 3 (Polyclonal), ALEXA Fluor 594

Anti-JNK1 + 3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit

Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	JNK1 + 3
Specificity	This antibody reacts specifically with JNK1 + 3
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Nucleus, Cytoplasm
Antigen Source	KLH conjugated synthetic peptide derived from human JNK1
Gene ID	5599
Swiss Prot	P45983
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Dog, Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, MAP2K4 and MAP2K7, Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity, The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis, The cell-permeable JNK inhibitory peptide may have promise as a therapeutic agent for diabetes, This kinase is activated by various cell stimuli, This kinase is also involved in UV radiation induced apoptosis, and are involved in a wide variety of cellular processes such as proliferation, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli, apoptosis and differentiation, differentiation, transcription regulation and development, which is thought to be related to cytochrome c-mediated cell death pathway, JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, JNK1(MAPK8) is a member of the MAP kinase family
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	JNK JNK1 SAPK1
Also known as	JNK1 + 3 Polyclonal Antibody
Other name	Anti-JNK1 + 3 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	JNK1 + 3
Short name	Anti-JNK1 + 3 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-JNK1 and 3 (polyclonal)
Alternative technique	polyclonals
Identity	6881
Gene	MAPK8
Long gene name	mitogen-activated protein kinase 8
Synonyms gene	PRKM8
Synonyms name	JUN N-terminal kinase
Locus	10q11, 22
Discovery year	1998-04-28
GenBank acession	L26318
Entrez gene record	5599
Pubmed identfication	8137421 8654373
Classification	Mitogen-activated protein kinases
Havana BLAST/BLAT	OTTHUMG00000018172

Anti-JNK1 + 3 (Polyclonal), ALEXA Fluor 594

Anti-JNK1 + 3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Similar products

Subscribe to our Newsletter