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Anti-JNK3 (Polyclonal), ALEXA Fluor 594

Anti-JNK3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideJNK3
SpecificityThis antibody reacts specifically with JNK3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human JNK3/MAPK10
Gene ID5602
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Beta-arrestin 2, Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs), Through its phosphorylation and nuclear localization, a receptor-regulated MAP kinase scaffold protein, and are involved in a wide variety of cellular processes such as proliferation, differentiation, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4), this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis, transcription regulation and development, which may be important in preventing neuronal apoptosis, MAPK10 (JNK3) is a member of the MAP kinase family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms JNK3 p493F12 p54bSAPK
Also known asJNK3 Polyclonal Antibody
Other nameAnti-JNK3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetJNK3
Short nameAnti-JNK3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-JNK3 (polyclonal)
Alternative techniquepolyclonals
Identity 6872
Gene MAPK10
Long gene name mitogen-activated protein kinase 10
Synonyms gene PRKM10
Locus 4q21, 3
Discovery year 1998-04-28
GenBank acession U07620
Entrez gene record 5602
Pubmed identfication 8654373 12436199
Classification Mitogen-activated protein kinases
Havana BLAST/BLAT OTTHUMG00000130604

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