Name : Anti-JNK3 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5832330101
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | JNK3 |
| Specificity | This antibody reacts specifically with JNK3 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human JNK3/MAPK10 |
| Gene ID | 5602 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Beta-arrestin 2, Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs), Through its phosphorylation and nuclear localization, a receptor-regulated MAP kinase scaffold protein, and are involved in a wide variety of cellular processes such as proliferation, differentiation, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4), this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis, transcription regulation and development, which may be important in preventing neuronal apoptosis, MAPK10 (JNK3) is a member of the MAP kinase family |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | JNK3 p493F12 p54bSAPK |
| Also known as | JNK3 Polyclonal Antibody |
| Other name | Anti-JNK3 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | JNK3 |
| Short name | Anti-JNK3 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-JNK3 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 6872 |
| Gene | MAPK10 |
| Long gene name | mitogen-activated protein kinase 10 |
| Synonyms gene | PRKM10 |
| Locus | 4q21, 3 |
| Discovery year | 1998-04-28 |
| GenBank acession | U07620 |
| Entrez gene record | 5602 |
| Pubmed identfication | 8654373 12436199 |
| Classification | Mitogen-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000130604 |